SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m5k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m5k PUTATIVE NADH
DEHYDROGENASE/NAD(P)
H NITROREDUCTASE
(Parabacteroides
distasonis) 		3 / 3 LEU A  90
TRP A 140
TYR A 146
 None
FMN  A 301 (-3.8A)
None
 1.02A 3aicA-3m5kA:
undetectable		 3aicA-3m5kA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m5k PUTATIVE NADH
DEHYDROGENASE/NAD(P)
H NITROREDUCTASE
(Parabacteroides
distasonis) 		3 / 3 LEU A  90
TRP A 140
TYR A 146
 None
FMN  A 301 (-3.8A)
None
 0.98A 3aicB-3m5kA:
undetectable		 3aicB-3m5kA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m5k PUTATIVE NADH
DEHYDROGENASE/NAD(P)
H NITROREDUCTASE
(Parabacteroides
distasonis) 		3 / 3 LEU A  90
TRP A 140
TYR A 146
 None
FMN  A 301 (-3.8A)
None
 0.99A 3aicE-3m5kA:
undetectable		 3aicE-3m5kA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m5k PUTATIVE NADH
DEHYDROGENASE/NAD(P)
H NITROREDUCTASE
(Parabacteroides
distasonis) 		3 / 3 LEU A  90
TRP A 140
TYR A 146
 None
FMN  A 301 (-3.8A)
None
 0.96A 3aicH-3m5kA:
undetectable		 3aicH-3m5kA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3m5k PUTATIVE NADH
DEHYDROGENASE/NAD(P)
H NITROREDUCTASE
(Parabacteroides
distasonis) 		4 / 6 TRP A 116
SER A 121
ALA A 122
ASP A 119
 None
 1.31A 3aruA-3m5kA:
undetectable		 3aruA-3m5kA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3m5k PUTATIVE NADH
DEHYDROGENASE/NAD(P)
H NITROREDUCTASE
(Parabacteroides
distasonis) 		4 / 8 GLU A  49
ASP A  54
ILE A  53
ILE A 103
 None
 0.82A 4kttD-3m5kA:
undetectable		 4kttD-3m5kA:
19.44