SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m5r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 9 MET A 104
ALA A 149
LEU A 147
LEU A 146
LEU A 119
 None
 1.21A 1ereD-3m5rA:
undetectable		 1ereD-3m5rA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		4 / 8 MET A 104
ALA A 149
LEU A 146
LEU A 119
 None
 0.94A 1ereE-3m5rA:
undetectable		 1ereE-3m5rA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		4 / 8 MET A 104
ALA A 149
LEU A 146
LEU A 119
 None
 0.95A 1ereF-3m5rA:
undetectable		 1ereF-3m5rA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 11 ALA A 177
GLU A 159
ARG A 118
ALA A 132
LEU A 144
 None
 1.17A 1mjlA-3m5rA:
undetectable
1mjlB-3m5rA:
undetectable		 1mjlA-3m5rA:
21.48
1mjlB-3m5rA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 11 GLY A 158
VAL A 192
ILE A 182
GLY A 184
ILE A 128
 None
 0.89A 1n49B-3m5rA:
undetectable		 1n49B-3m5rA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 11 GLY A 158
VAL A 192
ILE A 182
GLY A 184
ILE A 128
 None
 0.88A 1n49C-3m5rA:
undetectable		 1n49C-3m5rA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 12 GLY A 184
ILE A 128
VAL A 157
ILE A 160
VAL A 192
 None
 0.92A 3ucbB-3m5rA:
undetectable		 3ucbB-3m5rA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 10 ILE A 128
VAL A 157
ILE A 160
VAL A 194
VAL A 192
 None
 0.96A 4j5jB-3m5rA:
undetectable		 4j5jB-3m5rA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		4 / 8 ILE A 198
GLU A 186
ALA A 132
VAL A 178
 None
 0.75A 4jltA-3m5rA:
undetectable		 4jltA-3m5rA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 12 GLY A 179
ILE A 182
ILE A 112
LEU A 147
LEU A 119
 None
 1.05A 4pd4C-3m5rA:
undetectable		 4pd4C-3m5rA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 12 VAL A 194
GLY A 179
GLY A 158
GLY A 183
ILE A 182
 None
 0.90A 4q5mA-3m5rA:
undetectable		 4q5mA-3m5rA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 11 LEU A 181
LEU A 115
LEU A 147
ALA A 202
ILE A 198
 None
 1.14A 4x20D-3m5rA:
undetectable		 4x20D-3m5rA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3m5r NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		4 / 8 ASP A 173
ASN A 176
ALA A 177
VAL A 180
 None
 0.76A 4zbqA-3m5rA:
undetectable		 4zbqA-3m5rA:
13.91