SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 ILE A 201
PHE A  70
PHE A 243
PHE A 173
 None
 1.23A 1e72M-3m5uA:
undetectable		 1e72M-3m5uA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  74
GLY A 197
ASP A 167
PHE A 202
SER A 169
 MES  A 362 (-3.4A)
None
MES  A 362 (-3.1A)
None
MES  A 362 (-3.2A)
 1.23A 1wg8A-3m5uA:
undetectable		 1wg8A-3m5uA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 PHE A 173
LEU A  62
PHE A 243
SER A 230
 None
 1.19A 1wrlE-3m5uA:
undetectable		 1wrlE-3m5uA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 TYR A 335
SER A 333
THR A 148
ASN A 146
 None
None
MES  A 362 (-3.9A)
None
 1.42A 1yvpA-3m5uA:
2.1		 1yvpA-3m5uA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_A_PXLA1197_1
(ASPARTATE
AMINOTRANSFERASE)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 CYH A 144
THR A 148
ASP A 167
SER A 170
LYS A 191
 MES  A 362 ( 4.9A)
MES  A 362 (-3.9A)
MES  A 362 (-3.1A)
MES  A 362 ( 4.6A)
MES  A 362 (-2.8A)
 0.44A 2z9wA-3m5uA:
2.2		 2z9wA-3m5uA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_B_PXLB1197_1
(ASPARTATE
AMINOTRANSFERASE)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 CYH A 144
THR A 148
ASP A 167
SER A 170
LYS A 191
 MES  A 362 ( 4.9A)
MES  A 362 (-3.9A)
MES  A 362 (-3.1A)
MES  A 362 ( 4.6A)
MES  A 362 (-2.8A)
 0.45A 2z9wB-3m5uA:
7.1		 2z9wB-3m5uA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 ASN A 294
PHE A 309
GLY A 329
ILE A 299
PHE A 349
 None
 1.43A 3a25A-3m5uA:
2.6		 3a25A-3m5uA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 LEU A  15
GLN A  20
LEU A  18
GLU A  19
 None
 1.11A 3h5gA-3m5uA:
undetectable
3h5gB-3m5uA:
undetectable		 3h5gA-3m5uA:
7.48
3h5gB-3m5uA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 LEU A  69
GLY A 188
ALA A  75
ILE A  82
 None
None
MES  A 362 (-3.8A)
None
 0.73A 3jusA-3m5uA:
undetectable		 3jusA-3m5uA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 LEU A  69
GLY A 188
ALA A  75
ILE A  82
 None
None
MES  A 362 (-3.8A)
None
 0.73A 3jusA-3m5uA:
undetectable		 3jusA-3m5uA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 ASN A 244
ILE A 240
LEU A 198
ALA A  56
VAL A 189
 None
 1.01A 3rukA-3m5uA:
undetectable		 3rukA-3m5uA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 PHE A 126
ASP A 127
THR A 152
ILE A 129
 None
 0.82A 4pcuA-3m5uA:
undetectable		 4pcuA-3m5uA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 TYR A 241
GLU A  24
LEU A 245
GLN A  29
 None
 1.42A 4qztB-3m5uA:
undetectable		 4qztB-3m5uA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A 338
SER A 296
PHE A   6
ARG A 331
GLY A 320
 None
 1.36A 5il1A-3m5uA:
undetectable		 5il1A-3m5uA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 ILE A  35
PHE A 238
ILE A  17
LEU A  13
ILE A 195
 None
 0.96A 5mueA-3m5uA:
undetectable		 5mueA-3m5uA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 HIS A 260
ASN A 263
ALA A 267
 None
 0.37A 5n4tB-3m5uA:
undetectable		 5n4tB-3m5uA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 PHE A 126
ASP A 127
LEU A 292
 None
 0.76A 5uhcC-3m5uA:
undetectable		 5uhcC-3m5uA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 VAL A 113
LEU A  88
LEU A  86
ARG A 210
ILE A 165
 None
 1.46A 5xprA-3m5uA:
undetectable		 5xprA-3m5uA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3m5u PHOSPHOSERINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 VAL A  48
GLY A  51
PHE A 202
PHE A  70
VAL A 189
 None
 1.17A 6a94A-3m5uA:
undetectable		 6a94A-3m5uA:
21.29