SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3m65 ATP-DEPENDENT
PROTEASE LA 1
(Bacillus
subtilis) 		4 / 7 LEU A 191
VAL A 194
VAL A 154
ILE A 166
 None
 0.98A 1t87B-3m65A:
undetectable		 1t87B-3m65A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3m65 ATP-DEPENDENT
PROTEASE LA 1
(Bacillus
subtilis) 		3 / 3 GLY A  62
GLU A 103
ASP A  64
 None
 0.57A 2b25B-3m65A:
undetectable		 2b25B-3m65A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 3m65 ATP-DEPENDENT
PROTEASE LA 1
(Bacillus
subtilis) 		4 / 6 PRO A  13
LEU A  50
ARG A  15
GLY A  16
 None
 1.11A 2hs2B-3m65A:
undetectable		 2hs2B-3m65A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3m65 ATP-DEPENDENT
PROTEASE LA 1
(Bacillus
subtilis) 		3 / 3 LEU A  89
VAL A  29
ARG A  87
 None
 0.91A 3b0wB-3m65A:
undetectable		 3b0wB-3m65A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3m65 ATP-DEPENDENT
PROTEASE LA 1
(Bacillus
subtilis) 		4 / 5 ILE A  48
LEU A  17
HIS A  26
VAL A  88
 None
 1.04A 5jmnB-3m65A:
2.3		 5jmnB-3m65A:
11.76