SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m66'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 ILE A 215
LEU A 179
LEU A 178
LEU A 192
ILE A 188
 None
 1.07A 1fmlB-3m66A:
undetectable		 1fmlB-3m66A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 PHE A 264
LEU A 287
VAL A 280
LEU A 269
 None
 1.04A 1hk3A-3m66A:
undetectable		 1hk3A-3m66A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 VAL A 280
VAL A 281
THR A 288
THR A 276
 None
 0.85A 3bjwA-3m66A:
undetectable		 3bjwA-3m66A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 VAL A 280
VAL A 281
THR A 288
THR A 276
 None
 0.93A 3bjwG-3m66A:
undetectable		 3bjwG-3m66A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 VAL A 280
VAL A 281
THR A 288
THR A 276
 None
 0.96A 3bjwC-3m66A:
undetectable		 3bjwC-3m66A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 VAL A 280
VAL A 281
THR A 288
THR A 276
 None
 0.84A 3bjwD-3m66A:
undetectable		 3bjwD-3m66A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 THR A 210
ILE A 169
LYS A 168
GLU A 170
 None
 1.19A 4ac9C-3m66A:
undetectable		 4ac9C-3m66A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 THR A 210
ILE A 169
LYS A 168
GLU A 170
 None
 1.21A 4acaC-3m66A:
undetectable		 4acaC-3m66A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 THR A 210
ILE A 169
LYS A 168
GLU A 170
 None
 1.23A 4acbC-3m66A:
undetectable		 4acbC-3m66A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 11 ILE A 215
LEU A 166
LEU A 205
GLY A 206
PHE A 208
 None
 1.25A 4fogD-3m66A:
undetectable		 4fogD-3m66A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 258
LEU A 287
MET A 243
VAL A 244
HIS A 231
 None
 1.39A 4olmA-3m66A:
undetectable		 4olmA-3m66A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 LYS A 327
LEU A 330
PHE A 334
PHE A 355
 None
 0.86A 5b3sP-3m66A:
undetectable		 5b3sP-3m66A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3m66 MTERF
DOMAIN-CONTAINING
PROTEIN 1,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 ILE A 215
ILE A 169
MET A 191
 None
 0.67A 5i9yA-3m66A:
undetectable		 5i9yA-3m66A:
25.15