SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m6j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_B_ADNB1502_1 (CLASS B ACID PHOSPHATASE)	3m6j	UNCHARACTERIZED PROTEIN (Leptospirillum rubarum)	4 / 7	GLU A 52 TYR A 107 THR A 44 TYR A 67	None	1.15A	1rmtB-3m6jA: undetectable	1rmtB-3m6jA: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R2V_D_ACTD37_0 (GCN4 LEUCINE ZIPPER)	3m6j	UNCHARACTERIZED PROTEIN (Leptospirillum rubarum)	3 / 3	LYS A 124 ARG A 97 VAL A 96	None	0.94A	2r2vC-3m6jA: undetectable 2r2vD-3m6jA: undetectable	2r2vC-3m6jA: 14.07 2r2vD-3m6jA: 14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2REZ_A_ACTA156_0 (MULTIFUNCTIONAL CYCLASE-DEHYDRATASE- 3-O-METHYL TRANSFERASE TCMN)	3m6j	UNCHARACTERIZED PROTEIN (Leptospirillum rubarum)	4 / 7	GLU A 57 THR A 56 ARG A 50 LEU A 11	None	1.47A	2rezA-3m6jA: undetectable	2rezA-3m6jA: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WD9_C_IBPC1570_1 (ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL)	3m6j	UNCHARACTERIZED PROTEIN (Leptospirillum rubarum)	5 / 10	ILE A 130 LEU A 127 VAL A 123 GLY A 122 GLY A 33	None None None CL A 201 (-3.6A) None	1.13A	2wd9C-3m6jA: undetectable	2wd9C-3m6jA: 13.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RMT_B_ADNB1502_1","CLASS B ACID PHOSPHATASE","3m6j","UNCHARACTERIZED PROTEIN","Leptospirillum rubarum",4,"GLU A  52;TYR A 107;THR A  44;TYR A  67","None","1.15A","1rmtB-3m6jA:undetectable","1rmtB-3m6jA:22.37"],["2R2V_D_ACTD37_0","GCN4 LEUCINE ZIPPER","3m6j","UNCHARACTERIZED PROTEIN","Leptospirillum rubarum",3,"LYS A 124;ARG A  97;VAL A  96","None","0.94A","2r2vC-3m6jA:undetectable;2r2vD-3m6jA:undetectable","2r2vC-3m6jA:14.07;2r2vD-3m6jA:14.07"],["2REZ_A_ACTA156_0","MULTIFUNCTIONAL CYCLASE-DEHYDRATASE-3-O-METHYL TRANSFERASE TCMN","3m6j","UNCHARACTERIZED PROTEIN","Leptospirillum rubarum",4,"GLU A  57;THR A  56;ARG A  50;LEU A  11","None","1.47A","2rezA-3m6jA:undetectable","2rezA-3m6jA:22.53"],["2WD9_C_IBPC1570_1","ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL","3m6j","UNCHARACTERIZED PROTEIN","Leptospirillum rubarum",5,"ILE A 130;LEU A 127;VAL A 123;GLY A 122;GLY A  33","None;None;None; CL A 201 (-3.6A);None","1.13A","2wd9C-3m6jA:undetectable","2wd9C-3m6jA:13.74"]]