SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m6m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		4 / 8 ASN A  83
ASP A 105
GLY A  86
ASP A  87
 None
None
EDO  A 902 (-3.9A)
None
 0.90A 1bu5B-3m6mA:
undetectable		 1bu5B-3m6mA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 10 LEU A 136
VAL A 155
VAL A  81
GLY A 133
LEU A 194
 None
 1.32A 1fk9A-3m6mA:
undetectable		 1fk9A-3m6mA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 3m6m SENSORY/REGULATORY
PROTEIN RPFC
(Xanthomonas
campestris) 		4 / 6 HIS D 514
ASP D 468
MET D 515
PRO D 516
 None
MG  D 591 ( 4.4A)
None
None
 1.29A 1ilqA-3m6mD:
undetectable
1ilqC-3m6mD:
undetectable		 1ilqA-3m6mD:
19.26
1ilqC-3m6mD:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 10 LEU A 136
VAL A 155
VAL A  81
GLY A 133
LEU A 194
 None
 1.29A 1lw0A-3m6mA:
undetectable		 1lw0A-3m6mA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 ARG A  24
ILE A  19
TRP A  28
 None
 0.96A 1m8eB-3m6mA:
undetectable		 1m8eB-3m6mA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 ARG A  24
ILE A  19
TRP A  28
 None
 1.08A 1nodB-3m6mA:
undetectable		 1nodB-3m6mA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		4 / 6 GLY A 154
VAL A 209
ALA A 197
SER A 196
 IOD  A 290 (-4.3A)
None
IOD  A 290 ( 3.9A)
IOD  A 290 ( 4.2A)
 0.96A 1p6kA-3m6mA:
undetectable		 1p6kA-3m6mA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 ARG A  24
ILE A  19
TRP A  28
 None
 1.13A 1qomA-3m6mA:
undetectable		 1qomA-3m6mA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 3m6m RPFF PROTEIN
SENSORY/REGULATORY
PROTEIN RPFC
(Xanthomonas
campestris) 		4 / 8 MET D 530
LEU A 136
GLY A 137
LEU A 194
 None
None
EDO  A 902 (-3.6A)
None
 0.83A 1ya4A-3m6mD:
3.0		 1ya4A-3m6mD:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3m6m RPFF PROTEIN
SENSORY/REGULATORY
PROTEIN RPFC
(Xanthomonas
campestris) 		4 / 6 LEU D 521
ASN D 519
LEU D 498
LEU A 163
 None
 1.02A 1z95A-3m6mD:
undetectable		 1z95A-3m6mD:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		4 / 5 PRO A  71
GLY A  60
ASN A  64
GLY A 122
 None
 1.05A 1zlqA-3m6mA:
undetectable		 1zlqA-3m6mA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 ARG A  24
ILE A  19
TRP A  28
 None
 1.13A 2nodB-3m6mA:
undetectable		 2nodB-3m6mA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 ARG A  24
ILE A  19
TRP A  28
 None
 1.02A 3e68A-3m6mA:
undetectable		 3e68A-3m6mA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 ARG A  24
ILE A  19
TRP A  28
 None
 0.99A 3e6tB-3m6mA:
undetectable		 3e6tB-3m6mA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 ARG A  24
ILE A  19
TRP A  28
 None
 1.10A 3e7iB-3m6mA:
undetectable		 3e7iB-3m6mA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 12 VAL A 219
ARG A  24
LEU A 130
ILE A  52
PHE A 117
 None
 1.30A 3mnpA-3m6mA:
undetectable		 3mnpA-3m6mA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3m6m SENSORY/REGULATORY
PROTEIN RPFC
(Xanthomonas
campestris) 		5 / 12 GLY D 520
SER D 544
ASP D 468
ALA D 467
ASP D 522
 None
None
MG  D 591 ( 4.4A)
None
None
 1.26A 3nmuA-3m6mD:
undetectable
3nmuF-3m6mD:
undetectable		 3nmuA-3m6mD:
18.65
3nmuF-3m6mD:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		4 / 4 LEU A 121
GLY A 122
GLY A  60
THR A  57
 None
 0.81A 3si7A-3m6mA:
undetectable		 3si7A-3m6mA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		4 / 5 LEU A 144
LEU A 159
GLY A 158
GLY A 137
 None
None
None
EDO  A 902 (-3.6A)
 0.81A 3si7C-3m6mA:
undetectable
3si7D-3m6mA:
undetectable		 3si7C-3m6mA:
21.76
3si7D-3m6mA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 10 VAL A  73
HIS A 147
GLY A 120
ALA A 125
ALA A 123
 None
 1.01A 3ucjA-3m6mA:
undetectable		 3ucjA-3m6mA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 10 VAL A  73
HIS A 147
GLY A 120
ALA A 125
ALA A 123
 None
 1.01A 3ucjB-3m6mA:
undetectable		 3ucjB-3m6mA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3m6m RPFF PROTEIN
SENSORY/REGULATORY
PROTEIN RPFC
(Xanthomonas
campestris) 		4 / 7 LEU D 521
ASN D 519
LEU D 498
LEU A 163
 None
 1.01A 4okwA-3m6mD:
undetectable		 4okwA-3m6mD:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 9 PHE A 140
ALA A 143
PHE A 175
LEU A 205
VAL A 206
 None
 1.32A 4z69A-3m6mA:
1.3		 4z69A-3m6mA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 8 ALA A 142
PHE A  44
GLY A 139
ALA A 135
MET A  31
 None
 0.85A 4zjzA-3m6mA:
undetectable		 4zjzA-3m6mA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 11 PHE A  44
GLY A 139
TYR A 106
PHE A  91
GLY A 137
 None
None
None
None
EDO  A 902 (-3.6A)
 1.34A 5yjsA-3m6mA:
undetectable		 5yjsA-3m6mA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 HIS A 115
HIS A 118
ARG A 240
 None
 0.95A 6b58A-3m6mA:
undetectable		 6b58A-3m6mA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		3 / 3 GLU A  20
ASP A  25
PRO A  71
 None
 0.73A 6berA-3m6mA:
undetectable		 6berA-3m6mA:
3.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 3m6m RPFF PROTEIN
(Xanthomonas
campestris) 		5 / 12 GLN A  56
GLY A 113
ILE A 128
SER A 145
ALA A 143
 None
 1.18A 6c2mB-3m6mA:
undetectable		 6c2mB-3m6mA:
12.79