SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	3m6q	PEPTIDE DEFORMYLASE 1B (Arabidopsis thaliana)	4 / 6	PHE A 58 MET A 56 ILE A 130 VAL A 107	None None BB2 A 194 (-4.1A) None	1.35A	4mk4B-3m6qA: undetectable	4mk4B-3m6qA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N48_B_SAMB601_1 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	3m6q	PEPTIDE DEFORMYLASE 1B (Arabidopsis thaliana)	4 / 5	ASN A 52 PRO A 47 GLY A 50 ASP A 8	None	1.16A	4n48B-3m6qA: undetectable	4n48B-3m6qA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_A_SAMA501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	3m6q	PEPTIDE DEFORMYLASE 1B (Arabidopsis thaliana)	5 / 12	PRO A 47 GLY A 50 ASP A 8 LEU A 159 LEU A 162	None	1.06A	5wwsA-3m6qA: undetectable	5wwsA-3m6qA: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA609_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	3m6q	PEPTIDE DEFORMYLASE 1B (Arabidopsis thaliana)	3 / 3	HIS A 137 HIS A 133 ARG A 103	ZN A 195 ( 3.4A) ZN A 195 ( 3.3A) None	1.14A	6b58A-3m6qA: undetectable	6b58A-3m6qA: 17.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4MK4_B_CHDB502_0","FERROCHELATASE, MITOCHONDRIAL","3m6q","PEPTIDE DEFORMYLASE 1B","Arabidopsis thaliana",4,"PHE A  58;MET A  56;ILE A 130;VAL A 107","None;None;BB2 A 194 (-4.1A);None","1.35A","4mk4B-3m6qA:undetectable","4mk4B-3m6qA:18.18"],["4N48_B_SAMB601_1","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","3m6q","PEPTIDE DEFORMYLASE 1B","Arabidopsis thaliana",4,"ASN A  52;PRO A  47;GLY A  50;ASP A   8","None","1.16A","4n48B-3m6qA:undetectable","4n48B-3m6qA:20.28"],["5WWS_A_SAMA501_0","PUTATIVE METHYLTRANSFERASE NSUN6","3m6q","PEPTIDE DEFORMYLASE 1B","Arabidopsis thaliana",5,"PRO A  47;GLY A  50;ASP A   8;LEU A 159;LEU A 162","None","1.06A","5wwsA-3m6qA:undetectable","5wwsA-3m6qA:19.87"],["6B58_A_ACTA609_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","3m6q","PEPTIDE DEFORMYLASE 1B","Arabidopsis thaliana",3,"HIS A 137;HIS A 133;ARG A 103"," ZN A 195 ( 3.4A); ZN A 195 ( 3.3A);None","1.14A","6b58A-3m6qA:undetectable","6b58A-3m6qA:17.41"]]