SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m70'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		4 / 8 SER A 100
ASP A 149
PHE A 157
ASN A 151
 None
 1.08A 1lhvA-3m70A:
undetectable		 1lhvA-3m70A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		4 / 4 HIS A 109
VAL A 112
THR A 106
LEU A 136
 None
 1.42A 1oq5A-3m70A:
undetectable		 1oq5A-3m70A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		3 / 3 TRP A  14
VAL A  13
PRO A  12
 None
 0.85A 1rg1A-3m70A:
2.3		 1rg1A-3m70A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		3 / 3 TRP A  14
VAL A  13
PRO A  12
 None
 0.85A 1rh0A-3m70A:
2.2		 1rh0A-3m70A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		3 / 3 TRP A 148
LEU A 158
LYS A 162
 None
 1.00A 1yajK-3m70A:
undetectable		 1yajK-3m70A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		5 / 12 MET A 276
LEU A 264
VAL A 222
ALA A 223
MET A 195
 None
 1.19A 2c12C-3m70A:
undetectable		 2c12C-3m70A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		5 / 11 MET A 276
LEU A 264
VAL A 222
ALA A 223
MET A 195
 None
 1.10A 2c12F-3m70A:
undetectable		 2c12F-3m70A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		5 / 12 ASP A 126
LEU A 127
GLY A 128
GLY A 130
LEU A 197
 None
 0.86A 2nxeA-3m70A:
10.1		 2nxeA-3m70A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		5 / 12 ASP A 126
LEU A 127
GLY A 128
GLY A 130
LEU A 197
 None
 0.77A 2nxeB-3m70A:
15.6		 2nxeB-3m70A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		4 / 7 PHE A 194
PHE A 240
ILE A 205
ASN A 177
 None
 1.24A 2zseA-3m70A:
undetectable		 2zseA-3m70A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		5 / 12 ASP A 149
ILE A 155
SER A 154
ALA A 172
ASP A 175
 None
 1.21A 3axtA-3m70A:
13.0		 3axtA-3m70A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		5 / 12 ASP A 126
LEU A 127
GLY A 128
ASP A 149
LEU A 197
 None
 0.81A 3cjtC-3m70A:
14.9		 3cjtC-3m70A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		3 / 3 GLY A 130
ASP A 149
ASP A 175
 None
 0.28A 3ou7C-3m70A:
14.9		 3ou7C-3m70A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		4 / 7 THR A 280
HIS A 265
LEU A 264
SER A 190
 None
 1.08A 4pfjA-3m70A:
7.0		 4pfjA-3m70A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		5 / 12 GLY A 128
GLY A 130
ASP A 149
ASN A 151
LEU A 197
 None
 0.69A 5wy0A-3m70A:
14.0		 5wy0A-3m70A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3m70 TELLURITE RESISTANCE
PROTEIN TEHB HOMOLOG
(Haemophilus
influenzae) 		5 / 10 VAL A  78
LEU A  44
LEU A  85
LEU A  89
LEU A  37
 None
 0.99A 6f5uA-3m70A:
undetectable
6f5uB-3m70A:
undetectable		 6f5uA-3m70A:
14.89
6f5uB-3m70A:
15.52