SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m7f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3m7f E3 UBIQUITIN-PROTEIN
LIGASE NEDD4
(Mus
musculus) 		5 / 12 PHE B 178
LEU B 188
THR B 161
VAL B 144
ARG B 145
 None
 1.09A 2cbrA-3m7fB:
undetectable		 2cbrA-3m7fB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3m7f E3 UBIQUITIN-PROTEIN
LIGASE NEDD4
(Mus
musculus) 		4 / 7 PHE B 229
MET B 248
THR B 249
LEU B 213
 None
 1.03A 2eikA-3m7fB:
undetectable
2eikJ-3m7fB:
undetectable		 2eikA-3m7fB:
16.56
2eikJ-3m7fB:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 3m7f E3 UBIQUITIN-PROTEIN
LIGASE NEDD4
(Mus
musculus) 		4 / 7 GLN B 205
GLY B 204
VAL B 240
SER B 238
 None
 0.99A 4a3uB-3m7fB:
undetectable		 4a3uB-3m7fB:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 3m7f E3 UBIQUITIN-PROTEIN
LIGASE NEDD4
(Mus
musculus) 		5 / 12 PHE B 229
VAL B 208
ILE B 187
ILE B 176
PRO B 182
 None
 1.11A 4nnrA-3m7fB:
2.6
4nnrB-3m7fB:
2.7		 4nnrA-3m7fB:
20.99
4nnrB-3m7fB:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3m7f E3 UBIQUITIN-PROTEIN
LIGASE NEDD4
(Mus
musculus) 		5 / 11 LEU B 231
VAL B 206
VAL B 191
ALA B 127
LEU B 246
 None
 1.12A 6h1lB-3m7fB:
undetectable		 6h1lB-3m7fB:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 3m7f E3 UBIQUITIN-PROTEIN
LIGASE NEDD4
(Mus
musculus) 		3 / 3 ILE B 164
THR B 163
PRO B 170
 None
 0.58A 6ncsA-3m7fB:
undetectable		 6ncsA-3m7fB:
20.61