SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m7k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ESW_A_ACRA652_1 (AMYLOMALTASE)	3m7k	RESTRICTION ENDONUCLEASE PACI (Pseudomonas alcaligenes)	4 / 6	TYR A 100 GLY A 99 GLY A 41 SER A 96	None None None MG A 145 ( 4.7A)	0.99A	1eswA-3m7kA: undetectable	1eswA-3m7kA: 15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XCT_X_CPFX1020_1 (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)	3m7k	RESTRICTION ENDONUCLEASE PACI (Pseudomonas alcaligenes)	4 / 4	ARG A 61 GLY A 90 GLU A 70 SER A 34	None	1.26A	2xctS-3m7kA: undetectable 2xctU-3m7kA: undetectable	2xctS-3m7kA: 11.90 2xctU-3m7kA: 11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_A_GLYA717_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	3m7k	RESTRICTION ENDONUCLEASE PACI (Pseudomonas alcaligenes)	4 / 5	SER A 94 ARG A 106 ASP A 92 LYS A 116	None None MG A 145 (-3.4A) MG A 145 ( 4.2A)	1.26A	6dwdA-3m7kA: undetectable	6dwdA-3m7kA: 12.82