SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 11 LEU X  56
GLY X 171
GLY X 170
LEU X 203
LEU X   9
 None
 1.06A 1mx1A-3m7mX:
undetectable		 1mx1A-3m7mX:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 LEU X  47
LEU X  50
ALA X  53
LEU X  57
ILE X  33
 None
 1.09A 1s9pA-3m7mX:
undetectable		 1s9pA-3m7mX:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		4 / 6 LEU X 156
GLU X  49
LEU X 173
VAL X  26
 None
 1.19A 1sn5A-3m7mX:
undetectable		 1sn5A-3m7mX:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 11 ALA X  94
LEU X  30
LEU X  47
ASN X  45
LEU X  34
 None
 1.06A 2ceoA-3m7mX:
undetectable		 2ceoA-3m7mX:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 SER X  27
THR X  25
VAL X  24
LEU X 156
ILE X 158
 None
 1.44A 2fj1A-3m7mX:
undetectable		 2fj1A-3m7mX:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA X  94
LEU X  30
LEU X  47
ASN X  45
LEU X  34
 None
 1.07A 2riwA-3m7mX:
undetectable
2riwB-3m7mX:
undetectable		 2riwA-3m7mX:
21.97
2riwB-3m7mX:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA X  94
LEU X  30
LEU X  47
ASN X  45
LEU X  34
 None
 1.08A 2xn6A-3m7mX:
undetectable
2xn6B-3m7mX:
undetectable		 2xn6A-3m7mX:
20.79
2xn6B-3m7mX:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 ALA X  94
LEU X  30
LEU X  47
ASN X  45
LEU X  34
 None
 1.13A 2xn7A-3m7mX:
undetectable
2xn7B-3m7mX:
undetectable		 2xn7A-3m7mX:
21.63
2xn7B-3m7mX:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 LEU X  34
LEU X  30
ALA X  94
ALA X  48
LEU X 133
 None
 1.17A 3b0wA-3m7mX:
undetectable		 3b0wA-3m7mX:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		3 / 3 VAL X 163
LYS X 166
HIS X   6
 None
 0.86A 3elzA-3m7mX:
undetectable		 3elzA-3m7mX:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		5 / 12 LEU X 202
ARG X 213
GLY X 170
SER X  27
LEU X 205
 None
 1.09A 3okxB-3m7mX:
undetectable		 3okxB-3m7mX:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		4 / 5 THR X 137
GLU X 143
THR X 154
LEU X  57
 None
 1.35A 5utuH-3m7mX:
undetectable		 5utuH-3m7mX:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 3m7m 33 KDA CHAPERONIN
(Escherichia
coli) 		4 / 4 PHE X 146
LEU X  50
LEU X 156
VAL X 115
 None
 1.33A 5xxiA-3m7mX:
undetectable		 5xxiA-3m7mX:
17.63