SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		5 / 11 PHE D 191
ALA D 202
ALA D 108
LEU D 141
ALA D 144
 None
 1.11A 2bxeB-3m7nD:
undetectable		 2bxeB-3m7nD:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		4 / 5 ALA D 143
ALA D 190
ALA D 202
VAL D 112
 None
 0.80A 2nyrB-3m7nD:
undetectable		 2nyrB-3m7nD:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 3m7n PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 118
LEU A 139
ILE A  75
ARG A  64
 None
 1.06A 2rlfA-3m7nA:
undetectable
2rlfB-3m7nA:
undetectable		 2rlfA-3m7nA:
16.87
2rlfB-3m7nA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		4 / 8 GLY D  58
ASP D 124
ILE D 125
VAL D 153
 None
 0.73A 3fi0B-3m7nD:
undetectable		 3fi0B-3m7nD:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		4 / 8 GLY D  58
ASP D 124
ILE D 125
VAL D 153
 None
 0.66A 3fi0G-3m7nD:
undetectable		 3fi0G-3m7nD:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		4 / 8 GLY D  58
ASP D 124
ILE D 125
VAL D 153
 None
 0.73A 3fi0Q-3m7nD:
undetectable		 3fi0Q-3m7nD:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		4 / 5 LEU D 173
ALA D 163
MET D  47
ASN D 142
 None
 1.49A 3uq6A-3m7nD:
undetectable		 3uq6A-3m7nD:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		4 / 7 TYR A  23
GLU A  28
GLU A  25
GLU D 199
 None
 1.10A 4mi4A-3m7nA:
undetectable
4mi4C-3m7nA:
undetectable		 4mi4A-3m7nA:
21.96
4mi4C-3m7nA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 3m7n PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 168
ARG A 140
ASP A 116
VAL A 151
 None
 1.30A 4xqeA-3m7nA:
undetectable		 4xqeA-3m7nA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3m7n PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 168
ARG A 140
ASP A 116
VAL A 151
 None
 1.29A 4xqeB-3m7nA:
undetectable		 4xqeB-3m7nA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3m7n PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		4 / 7 ALA A  32
GLY A  21
SER A  48
GLY A  35
 None
 0.74A 5e26A-3m7nA:
undetectable
5e26B-3m7nA:
undetectable		 5e26A-3m7nA:
18.82
5e26B-3m7nA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3m7n PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		4 / 7 GLY A  21
SER A  48
GLY A  35
ALA A  32
 None
 0.76A 5e26C-3m7nA:
undetectable
5e26D-3m7nA:
undetectable		 5e26C-3m7nA:
18.82
5e26D-3m7nA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		5 / 12 GLU D 214
GLU D 184
LEU D 171
GLY D 183
ALA D 185
 None
 1.21A 5e3iA-3m7nD:
undetectable		 5e3iA-3m7nD:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		3 / 3 VAL D 104
SER D 161
MET D 158
 None
 0.91A 5ikqA-3m7nD:
0.4		 5ikqA-3m7nD:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
(Archaeoglobus
fulgidus) 		3 / 3 LYS D  49
ASP D 133
ARG D  21
 None
 0.92A 5jwaA-3m7nD:
undetectable
5jwaH-3m7nD:
undetectable		 5jwaA-3m7nD:
19.85
5jwaH-3m7nD:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3m7n PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		3 / 3 ARG A  85
ARG D  60
ARG D  38
 None
 0.99A 5vcgA-3m7nA:
undetectable		 5vcgA-3m7nA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3m7n PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  95
ILE A  75
GLY A  93
ILE A 108
ASP A  67
 None
 1.02A 6emuB-3m7nA:
undetectable		 6emuB-3m7nA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3m7n PUTATIVE
UNCHARACTERIZED
PROTEIN AF_0206
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  95
ILE A  75
GLY A  93
ILE A 108
ASP A  67
 None
 1.03A 6emuC-3m7nA:
undetectable		 6emuC-3m7nA:
23.25