SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		5 / 12 ALA A  32
LEU A  83
ILE A  85
PHE A  70
PHE A  51
 None
None
L9R  A 301 (-4.6A)
L9R  A 301 ( 4.3A)
None
 1.37A 1y0xX-3m7oA:
undetectable		 1y0xX-3m7oA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		4 / 8 TYR A 145
ASP A  84
SER A  98
TYR A  97
 BEN  A 165 (-3.4A)
BEN  A 163 ( 3.2A)
BEN  A 163 ( 3.4A)
L9R  A 301 ( 3.5A)
 0.95A 2bteA-3m7oA:
undetectable		 2bteA-3m7oA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		4 / 8 TYR A 145
ASP A  84
SER A  98
TYR A  97
 BEN  A 165 (-3.4A)
BEN  A 163 ( 3.2A)
BEN  A 163 ( 3.4A)
L9R  A 301 ( 3.5A)
 0.95A 2bteD-3m7oA:
undetectable		 2bteD-3m7oA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		4 / 8 TYR A 145
ASP A  84
SER A  98
TYR A  97
 BEN  A 165 (-3.4A)
BEN  A 163 ( 3.2A)
BEN  A 163 ( 3.4A)
L9R  A 301 ( 3.5A)
 0.94A 2v0gA-3m7oA:
undetectable		 2v0gA-3m7oA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		3 / 3 LEU A  48
TRP A  27
GLY A  26
 None
 0.76A 3l35A-3m7oA:
undetectable
3l35H-3m7oA:
undetectable		 3l35A-3m7oA:
11.54
3l35H-3m7oA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		3 / 3 LEU A  48
TRP A  27
GLY A  26
 None
 0.77A 3l35B-3m7oA:
undetectable
3l35K-3m7oA:
undetectable		 3l35B-3m7oA:
11.54
3l35K-3m7oA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		5 / 12 LEU A  53
LEU A 142
ALA A 157
VAL A  40
ALA A  32
 None
L9R  A 301 (-4.0A)
None
None
None
 1.17A 4x1iB-3m7oA:
undetectable		 4x1iB-3m7oA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		5 / 12 LEU A  53
LEU A 142
ALA A 157
VAL A  40
ALA A  32
 None
L9R  A 301 (-4.0A)
None
None
None
 1.01A 4x1yD-3m7oA:
undetectable		 4x1yD-3m7oA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		4 / 7 VAL A  40
LEU A  38
ALA A  32
LEU A 142
 None
None
None
L9R  A 301 (-4.0A)
 0.66A 5jq7A-3m7oA:
undetectable		 5jq7A-3m7oA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		5 / 10 PRO A 107
LEU A  81
PHE A 111
ALA A 153
PHE A  70
 None
None
None
L9R  A 301 (-3.6A)
L9R  A 301 ( 4.3A)
 0.89A 5m0oA-3m7oA:
undetectable		 5m0oA-3m7oA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3m7o LYMPHOCYTE ANTIGEN
86
(Mus
musculus) 		4 / 8 LEU A  81
PHE A 111
ALA A 153
PHE A  70
 None
None
L9R  A 301 (-3.6A)
L9R  A 301 ( 4.3A)
 0.68A 5m0oC-3m7oA:
undetectable		 5m0oC-3m7oA:
14.91