SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		5 / 11 GLY G  54
PHE G  32
ASP G 150
ALA G 151
ASP G  55
 None
 1.25A 3id5B-3m85G:
undetectable		 3id5B-3m85G:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		5 / 11 GLY G  54
PHE G  32
ASP G 150
ALA G 151
ASP G  55
 None
 1.25A 3id5F-3m85G:
undetectable		 3id5F-3m85G:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		5 / 12 ASN G  82
ASP G 138
ILE G 139
ALA G 141
VAL G  58
 None
 1.19A 4dx5B-3m85G:
undetectable		 4dx5B-3m85G:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		4 / 6 ARG G  33
GLU G 203
ASP G 145
ASP G 144
 None
 1.07A 4kcnA-3m85G:
undetectable		 4kcnA-3m85G:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		4 / 6 ARG G  33
GLU G 203
ASP G 145
ASP G 144
 None
 1.06A 4kcnB-3m85G:
undetectable		 4kcnB-3m85G:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		5 / 12 LEU G 105
ASN G 147
ALA G  49
VAL G  58
VAL G  51
 None
 0.90A 4nkxB-3m85G:
undetectable		 4nkxB-3m85G:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_1
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		4 / 4 SER G 228
GLU G 100
GLU G  94
ASP G 209
 None
 1.32A 4pclB-3m85G:
0.0		 4pclB-3m85G:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		5 / 9 LEU G 190
SER G 189
LEU G 241
GLY G 229
LEU G 233
 None
 0.98A 4rs0A-3m85G:
undetectable		 4rs0A-3m85G:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3m85 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2
(Archaeoglobus
fulgidus) 		5 / 10 SER G 189
VAL G 108
GLY G 112
SER G 116
VAL G 185
 None
 1.45A 6hu9L-3m85G:
undetectable
6hu9P-3m85G:
undetectable
6hu9T-3m85G:
undetectable		 6hu9L-3m85G:
21.86
6hu9P-3m85G:
19.92
6hu9T-3m85G:
15.32