SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m8l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 THR A 131
PRO A 133
THR A 132
 None
 0.88A 1a7yB-3m8lA:
undetectable		 1a7yB-3m8lA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		5 / 12 GLY A 616
VAL A 176
LEU A 188
ASP A 620
ALA A 658
 None
 1.44A 1e3vA-3m8lA:
undetectable		 1e3vA-3m8lA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 THR A 132
THR A 131
PRO A 133
 None
 0.85A 1i3wF-3m8lA:
undetectable		 1i3wF-3m8lA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_A_CLWA906_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		4 / 5 PRO A 421
VAL A 548
TYR A 467
MET A 466
 None
 1.25A 1m8dA-3m8lA:
undetectable		 1m8dA-3m8lA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_B_CLWB907_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		4 / 5 PRO A 421
VAL A 548
TYR A 467
MET A 466
 None
 1.26A 1m8dB-3m8lA:
undetectable		 1m8dB-3m8lA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_A_CLWA906_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		4 / 5 PRO A 421
VAL A 547
TYR A 467
MET A 466
 None
 1.49A 1m9jA-3m8lA:
undetectable		 1m9jA-3m8lA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 THR A 132
THR A 131
PRO A 133
 None
 0.84A 1qfiA-3m8lA:
undetectable		 1qfiA-3m8lA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		5 / 9 ALA A 232
TYR A 292
LEU A 231
TRP A 178
GLY A 229
 None
 1.45A 1rulH-3m8lA:
undetectable
1rulL-3m8lA:
1.4		 1rulH-3m8lA:
17.42
1rulL-3m8lA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 THR A 132
THR A 131
PRO A 133
 None
 0.84A 1unjF-3m8lA:
undetectable		 1unjF-3m8lA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		5 / 12 PHE A 641
LEU A 529
GLY A 351
ASN A 584
ILE A 350
 None
 1.32A 2e7fA-3m8lA:
undetectable		 2e7fA-3m8lA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		4 / 7 TRP A 420
SER A 471
CYH A 469
ILE A 487
 None
 1.01A 2xz5A-3m8lA:
undetectable
2xz5B-3m8lA:
undetectable		 2xz5A-3m8lA:
18.62
2xz5B-3m8lA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 LEU A 527
TRP A 383
TYR A 467
 None
 0.92A 3aicA-3m8lA:
undetectable		 3aicA-3m8lA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 LEU A 527
TRP A 383
TYR A 467
 None
 0.96A 3aicB-3m8lA:
undetectable		 3aicB-3m8lA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 LEU A 527
TRP A 383
TYR A 467
 None
 0.98A 3aicE-3m8lA:
undetectable		 3aicE-3m8lA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 LEU A 527
TRP A 383
TYR A 467
 None
 0.95A 3aicG-3m8lA:
undetectable		 3aicG-3m8lA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		3 / 3 LEU A 527
TRP A 383
TYR A 467
 None
 0.97A 3aicH-3m8lA:
undetectable		 3aicH-3m8lA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		4 / 8 HIS A 563
GLY A 632
ASN A 562
ARG A 656
 None
 1.25A 3ccfA-3m8lA:
undetectable		 3ccfA-3m8lA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		5 / 12 ILE A 456
THR A 461
GLY A 536
VAL A 576
ILE A 437
 None
 1.06A 4c9lB-3m8lA:
undetectable		 4c9lB-3m8lA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		5 / 12 ILE A 456
THR A 461
GLY A 536
VAL A 576
ILE A 437
 None
 1.07A 4c9oA-3m8lA:
undetectable		 4c9oA-3m8lA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		5 / 12 ILE A 456
THR A 461
GLY A 536
VAL A 576
ILE A 437
 None
 1.07A 4c9oB-3m8lA:
undetectable		 4c9oB-3m8lA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3m8l CAPSID PROTEIN
(Feline
calicivirus) 		4 / 7 ILE A 550
GLY A 382
PHE A 566
ASP A 422
 None
 1.12A 5hieA-3m8lA:
undetectable		 5hieA-3m8lA:
20.67