SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m8n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 3m8n POSSIBLE GLUTATHIONE
S-TRANSFERASE
(Rhodopseudomonas
palustris) 		5 / 12 THR A 193
ARG A  17
VAL A 190
LEU A  80
ILE A 158
 None
 1.33A 1kqwA-3m8nA:
undetectable		 1kqwA-3m8nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 3m8n POSSIBLE GLUTATHIONE
S-TRANSFERASE
(Rhodopseudomonas
palustris) 		4 / 5 ALA A 162
ILE A 158
ASN A  68
ILE A  70
 None
 1.06A 2h4jA-3m8nA:
undetectable		 2h4jA-3m8nA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3m8n POSSIBLE GLUTATHIONE
S-TRANSFERASE
(Rhodopseudomonas
palustris) 		5 / 12 ILE A 106
VAL A 183
TRP A 186
LEU A 187
ALA A 162
 None
 1.20A 2jj8C-3m8nA:
undetectable		 2jj8C-3m8nA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3m8n POSSIBLE GLUTATHIONE
S-TRANSFERASE
(Rhodopseudomonas
palustris) 		4 / 5 GLU A 103
PHE A 111
TYR A 166
HIS A 168
 None
 1.45A 4a97J-3m8nA:
undetectable		 4a97J-3m8nA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3m8n POSSIBLE GLUTATHIONE
S-TRANSFERASE
(Rhodopseudomonas
palustris) 		4 / 6 TYR A 164
ASP A 171
ILE A 106
TYR A 110
 None
 1.39A 5igyA-3m8nA:
undetectable		 5igyA-3m8nA:
21.45