SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m8o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		4 / 6 ARG H 170
THR H 168
VAL H 167
LEU H 191
 None
 1.03A 2e1qA-3m8oH:
undetectable		 2e1qA-3m8oH:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		4 / 6 ARG H 170
THR H 168
VAL H 167
LEU H 191
 None
 0.99A 2e1qC-3m8oH:
undetectable		 2e1qC-3m8oH:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 GLY H 110
ALA H  23
ALA H  81
VAL H  37
LEU H  20
 None
 0.96A 2yqzA-3m8oH:
undetectable		 2yqzA-3m8oH:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 ARG H 170
THR H 168
VAL H 167
LEU H 191
 None
 0.95A 3ax7A-3m8oH:
undetectable		 3ax7A-3m8oH:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ARG H 170
THR H 168
VAL H 167
LEU H 191
 None
 0.91A 3uniA-3m8oH:
undetectable		 3uniA-3m8oH:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		4 / 8 ARG H 170
THR H 168
VAL H 167
LEU H 191
 None
 0.94A 3uniB-3m8oH:
undetectable		 3uniB-3m8oH:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ASP H  91
ARG H  69
LYS H  89
 None
 1.07A 3wipG-3m8oH:
2.6		 3wipG-3m8oH:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSG_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		5 / 9 VAL H  99
GLY H  31
SER H  32
LEU H  29
THR H  28
 None
 1.41A 5ksgB-3m8oH:
undetectable		 5ksgB-3m8oH:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KT8_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		5 / 9 VAL H  99
GLY H  31
SER H  32
LEU H  29
THR H  28
 None
 1.44A 5kt8B-3m8oH:
undetectable		 5kt8B-3m8oH:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXS_B_NIZB806_1
(CATALASE-PEROXIDASE)		 3m8o IMMUNOGLOBULIN A1
HEAVY CHAIN
(Homo
sapiens) 		5 / 9 VAL H  99
GLY H  31
SER H  32
LEU H  29
THR H  28
 None
 1.43A 5sxsB-3m8oH:
undetectable		 5sxsB-3m8oH:
15.10