SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m8y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 SER A 157
VAL A 191
GLY A 192
LEU A 217
GLU A 182
 None
 1.40A 1a27A-3m8yA:
undetectable		 1a27A-3m8yA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 PHE A 366
GLY A  88
PHE A  26
ASP A  22
ALA A  20
 None
TPO  A  85 ( 3.8A)
None
None
None
 1.08A 1e3vA-3m8yA:
undetectable		 1e3vA-3m8yA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_B_DXCB801_0
(STEROID
DELTA-ISOMERASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 11 PHE A 366
GLY A  88
PHE A  26
ASP A  22
ALA A  20
 None
TPO  A  85 ( 3.8A)
None
None
None
 1.09A 1e3vB-3m8yA:
0.0		 1e3vB-3m8yA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 5 ASP A 286
HIS A 291
HIS A 328
HIS A 339
 MN  A 395 (-2.2A)
MN  A 395 (-3.4A)
MN  A 396 (-3.3A)
MN  A 395 (-3.4A)
 0.43A 1ei6A-3m8yA:
15.3		 1ei6A-3m8yA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 8 ASP A  13
ASP A 286
HIS A 291
HIS A 328
HIS A 339
 MN  A 396 (-2.0A)
MN  A 395 (-2.2A)
MN  A 395 (-3.4A)
MN  A 396 (-3.3A)
MN  A 395 (-3.4A)
 0.49A 1ei6C-3m8yA:
16.0		 1ei6C-3m8yA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 8 SER A  14
VAL A  15
LEU A 302
MET A  46
 None
 1.08A 1fduB-3m8yA:
undetectable		 1fduB-3m8yA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 6 SER A 157
GLY A 192
LEU A 217
GLU A 182
 None
 0.97A 1fduD-3m8yA:
undetectable		 1fduD-3m8yA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 9 ASN A 390
LEU A 392
ALA A 348
LEU A 321
LEU A 323
 None
 1.49A 1hwiA-3m8yA:
2.3		 1hwiA-3m8yA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 LEU A   9
HIS A  89
PHE A 366
THR A 325
ARG A 341
 None
TPO  A  85 ( 4.0A)
None
None
None
 1.38A 1ia0B-3m8yA:
undetectable		 1ia0B-3m8yA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 LEU A   9
HIS A  89
PHE A 366
THR A 325
GLY A 329
 None
TPO  A  85 ( 4.0A)
None
None
None
 1.28A 1ia0B-3m8yA:
undetectable		 1ia0B-3m8yA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 6 PRO A 295
ALA A 301
GLU A 304
GLU A 300
 None
 1.47A 1qhyA-3m8yA:
3.0		 1qhyA-3m8yA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 7 GLN A 160
ALA A 162
PHE A 108
ARG A 181
 None
 1.22A 1t9wA-3m8yA:
undetectable		 1t9wA-3m8yA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 LEU A   9
HIS A  89
PHE A 366
THR A 325
ARG A 341
 None
TPO  A  85 ( 4.0A)
None
None
None
 1.38A 1tubB-3m8yA:
undetectable		 1tubB-3m8yA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 LEU A   9
HIS A  89
PHE A 366
THR A 325
GLY A 329
 None
TPO  A  85 ( 4.0A)
None
None
None
 1.28A 1tubB-3m8yA:
undetectable		 1tubB-3m8yA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 5 LEU A 136
ILE A 150
LEU A 149
SER A 148
 None
 1.00A 2byoA-3m8yA:
undetectable		 2byoA-3m8yA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 VAL A  10
PHE A 279
ILE A   7
LEU A 392
ASP A 368
 None
None
None
None
GOL  A 401 (-2.8A)
 1.45A 2iyfB-3m8yA:
undetectable		 2iyfB-3m8yA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 6 GLY A  53
PRO A 345
LYS A  75
THR A  74
 None
None
ACT  A 399 ( 4.6A)
ACT  A 399 (-4.3A)
 1.31A 2m2oB-3m8yA:
undetectable		 2m2oB-3m8yA:
4.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 9 THR A 223
TYR A 245
PHE A 279
GLY A 370
ALA A 367
 None
 1.15A 3jusB-3m8yA:
undetectable		 3jusB-3m8yA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		3 / 3 SER A 131
GLY A 132
THR A 133
 None
 0.12A 3k9wA-3m8yA:
undetectable		 3k9wA-3m8yA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 4 VAL A 312
PHE A   8
PHE A 279
VAL A  11
 None
 1.39A 3rv5C-3m8yA:
undetectable
3rv5D-3m8yA:
undetectable		 3rv5C-3m8yA:
12.50
3rv5D-3m8yA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_A_DAHA351_1
(PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 9 HIS A 334
SER A  31
ARG A 293
GLU A 342
GLY A 329
 MN  A 397 (-3.4A)
None
None
None
None
 1.27A 3tehA-3m8yA:
0.1		 3tehA-3m8yA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 6 ARG A 197
GLN A 160
TYR A 152
LEU A 136
 None
 1.37A 3tgvB-3m8yA:
undetectable		 3tgvB-3m8yA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 PHE A 313
ILE A  34
PHE A 285
ALA A 301
ALA A 307
 None
 1.20A 3ua1A-3m8yA:
1.9		 3ua1A-3m8yA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 11 HIS A 328
GLY A  88
PHE A 279
GLY A 239
MET A 225
 MN  A 396 (-3.3A)
TPO  A  85 ( 3.8A)
None
None
None
 1.20A 3v3nD-3m8yA:
undetectable		 3v3nD-3m8yA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 8 ILE A  63
LEU A  44
VAL A  15
GLY A  16
 None
 0.86A 3w1wA-3m8yA:
undetectable		 3w1wA-3m8yA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 11 SER A 157
VAL A 194
LEU A 159
GLU A 182
ALA A 180
 None
 1.17A 4e0fA-3m8yA:
undetectable		 4e0fA-3m8yA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 5 HIS A 334
THR A  33
GLU A 342
HIS A 328
 MN  A 397 (-3.4A)
None
None
MN  A 396 (-3.3A)
 1.24A 4hvcB-3m8yA:
undetectable		 4hvcB-3m8yA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 7 ASP A  32
THR A 340
GLN A 303
LEU A 302
 GOL  A 400 ( 4.4A)
None
None
None
 1.13A 4ib4A-3m8yA:
undetectable		 4ib4A-3m8yA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 11 HIS A 339
ASP A 156
ASP A  13
ASP A 243
ILE A 244
 MN  A 395 (-3.4A)
MN  A 395 (-2.1A)
MN  A 396 (-2.0A)
None
TPO  A  85 ( 4.3A)
 1.36A 4ktvC-3m8yA:
undetectable
4ktvD-3m8yA:
undetectable		 4ktvC-3m8yA:
24.29
4ktvD-3m8yA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 6 GLU A 117
THR A 120
THR A 184
ASN A 127
 None
 1.19A 4pfjB-3m8yA:
undetectable		 4pfjB-3m8yA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 6 PHE A  26
SER A  31
HIS A 334
LEU A  29
 None
None
MN  A 397 (-3.4A)
None
 1.42A 5dzka-3m8yA:
undetectable
5dzko-3m8yA:
undetectable		 5dzka-3m8yA:
21.17
5dzko-3m8yA:
1.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 11 VAL A  15
THR A 340
GLU A 342
TYR A 298
LEU A 302
 None
 1.03A 5jh7B-3m8yA:
undetectable		 5jh7B-3m8yA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 11 VAL A  15
THR A 340
GLU A 342
TYR A 298
LEU A 302
 None
 0.97A 5jh7D-3m8yA:
undetectable		 5jh7D-3m8yA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 GLY A 329
ASP A  32
ILE A  34
GLY A 290
HIS A 334
 None
GOL  A 400 ( 4.4A)
None
None
MN  A 397 (-3.4A)
 0.93A 5kb6B-3m8yA:
undetectable		 5kb6B-3m8yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 8 ASP A 286
ASP A  13
VAL A  11
GLY A  16
ILE A  34
 MN  A 395 (-2.2A)
MN  A 396 (-2.0A)
None
None
None
 1.36A 5kr1B-3m8yA:
undetectable		 5kr1B-3m8yA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 LEU A  52
LEU A  70
GLY A  71
GLY A 357
LEU A 316
 None
 0.90A 5uc1A-3m8yA:
undetectable		 5uc1A-3m8yA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 LEU A  52
LEU A  70
GLY A  71
GLY A 357
LEU A 316
 None
 0.94A 5uc1B-3m8yA:
undetectable		 5uc1B-3m8yA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		5 / 12 PHE A 313
ILE A  34
PHE A 285
ALA A 301
ALA A 307
 None
 1.20A 5vcgA-3m8yA:
1.7		 5vcgA-3m8yA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		3 / 3 THR A  33
GLU A 342
HIS A 328
 None
None
MN  A 396 (-3.3A)
 0.92A 5xioA-3m8yA:
undetectable		 5xioA-3m8yA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		3 / 3 THR A  33
GLU A 342
HIS A 328
 None
None
MN  A 396 (-3.3A)
 0.90A 5xiqB-3m8yA:
2.5		 5xiqB-3m8yA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		3 / 3 THR A  33
GLU A 342
HIS A 328
 None
None
MN  A 396 (-3.3A)
 0.91A 5xiqD-3m8yA:
undetectable		 5xiqD-3m8yA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		3 / 3 ARG A 193
LYS A  86
ARG A 212
 None
TPO  A  85 ( 2.9A)
None
 1.45A 6az3C-3m8yA:
undetectable
6az3L-3m8yA:
undetectable
6az3M-3m8yA:
undetectable		 6az3C-3m8yA:
11.02
6az3L-3m8yA:
10.70
6az3M-3m8yA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 5 GLU A 391
PHE A 388
ASP A 368
THR A 372
 None
None
GOL  A 401 (-2.8A)
None
 1.33A 6b58A-3m8yA:
undetectable		 6b58A-3m8yA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 5 THR A  33
HIS A 328
ASP A 286
HIS A 339
 None
MN  A 396 (-3.3A)
MN  A 395 (-2.2A)
MN  A 395 (-3.4A)
 1.34A 6dchA-3m8yA:
undetectable		 6dchA-3m8yA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 3m8y PHOSPHOPENTOMUTASE
(Bacillus
cereus) 		4 / 6 PRO A 219
TRP A  90
ILE A  97
GLY A 221
 None
 1.11A 6gqiA-3m8yA:
undetectable		 6gqiA-3m8yA:
20.48