SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_C_DVAC8_0 (GRAMICIDIN A)	3m94	TRANSLATION INITIATION FACTOR 4E (Ascaris suum)	3 / 4	VAL A 176 TRP A 179 TRP A 143	None	1.44A	1gmkC-3m94A: undetectable 1gmkD-3m94A: undetectable	1gmkC-3m94A: 8.27 1gmkD-3m94A: 8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IGT_C_SAMC1003_1 (SAM DEPENDENT METHYLTRANSFERASE)	3m94	TRANSLATION INITIATION FACTOR 4E (Ascaris suum)	4 / 4	ASP A 174 ASP A 140 ASP A 103 GLY A 97	None None M7M A 1 ( 4.4A) None	1.12A	2igtC-3m94A: undetectable	2igtC-3m94A: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RAV_A_RAVA183_1 (FERRITIN LIGHT CHAIN)	3m94	TRANSLATION INITIATION FACTOR 4E (Ascaris suum)	4 / 6	LEU A 146 TYR A 142 ALA A 95 LEU A 200	None	1.02A	3ravA-3m94A: undetectable	3ravA-3m94A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0B_A_NVPA901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	3m94	TRANSLATION INITIATION FACTOR 4E (Ascaris suum)	4 / 8	LEU A 147 VAL A 176 TYR A 104 LEU A 58	None	1.15A	4q0bA-3m94A: 3.6	4q0bA-3m94A: 14.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GMK_C_DVAC8_0","GRAMICIDIN A","3m94","TRANSLATION INITIATION FACTOR 4E","Ascaris suum",3,"VAL A 176;TRP A 179;TRP A 143","None","1.44A","1gmkC-3m94A:undetectable;1gmkD-3m94A:undetectable","1gmkC-3m94A:8.27;1gmkD-3m94A:8.27"],["2IGT_C_SAMC1003_1","SAM DEPENDENT METHYLTRANSFERASE","3m94","TRANSLATION INITIATION FACTOR 4E","Ascaris suum",4,"ASP A 174;ASP A 140;ASP A 103;GLY A  97","None;None;M7M A   1 ( 4.4A);None","1.12A","2igtC-3m94A:undetectable","2igtC-3m94A:20.58"],["3RAV_A_RAVA183_1","FERRITIN LIGHT CHAIN","3m94","TRANSLATION INITIATION FACTOR 4E","Ascaris suum",4,"LEU A 146;TYR A 142;ALA A  95;LEU A 200","None","1.02A","3ravA-3m94A:undetectable","3ravA-3m94A:20.00"],["4Q0B_A_NVPA901_1","HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","3m94","TRANSLATION INITIATION FACTOR 4E","Ascaris suum",4,"LEU A 147;VAL A 176;TYR A 104;LEU A  58","None","1.15A","4q0bA-3m94A:3.6","4q0bA-3m94A:14.65"]]