SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_D_BEZD2002_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 3m9g PROTEIN KINASE
(Staphylococcus
aureus) 		5 / 9 PHE A 536
LEU A 531
PHE A 519
GLY A 560
ASP A 564
 None
 1.39A 2ok6B-3m9gA:
0.0
2ok6D-3m9gA:
0.0		 2ok6B-3m9gA:
21.47
2ok6D-3m9gA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 3m9g PROTEIN KINASE
(Staphylococcus
aureus) 		5 / 10 PHE A 536
LEU A 531
PHE A 519
GLY A 560
ASP A 564
 None
 1.40A 2ok6A-3m9gA:
undetectable
2ok6H-3m9gA:
undetectable		 2ok6A-3m9gA:
21.47
2ok6H-3m9gA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 3m9g PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 5 ILE A 383
SER A 386
LYS A 385
GLY A 384
 None
 1.10A 3tkdB-3m9gA:
undetectable		 3tkdB-3m9gA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3m9g PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 5 ILE A 383
SER A 386
LYS A 385
GLY A 384
 None
 1.10A 3tkdA-3m9gA:
undetectable		 3tkdA-3m9gA:
21.54