SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m9i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		5 / 11 LEU A 170
LEU A 168
ALA A 186
MET A 183
LEU A 137
 None
 1.42A 1kt7A-3m9iA:
undetectable		 1kt7A-3m9iA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		5 / 12 GLY A  96
PHE A  18
VAL A  67
ALA A 186
ALA A  97
 None
 1.31A 2avdB-3m9iA:
undetectable		 2avdB-3m9iA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		6 / 10 PHE A  26
GLY A  96
GLY A  27
LEU A  28
LEU A 104
ALA A 101
 None
 1.27A 2v3kA-3m9iA:
undetectable		 2v3kA-3m9iA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		5 / 12 PHE A 136
VAL A 206
GLY A 207
GLY A 211
THR A 131
 None
 1.37A 3dh0A-3m9iA:
undetectable		 3dh0A-3m9iA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		3 / 3 ASN A 184
ASN A 119
GLU A 134
 None
 0.92A 3kpdB-3m9iA:
undetectable		 3kpdB-3m9iA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		5 / 12 VAL A  90
GLN A  93
LEU A  52
ALA A 186
ASN A 184
 None
 1.23A 4qckA-3m9iA:
undetectable		 4qckA-3m9iA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		5 / 10 ASP A 150
ALA A  74
TYR A 219
PHE A  75
GLY A  78
 None
 1.30A 4xp1A-3m9iA:
undetectable		 4xp1A-3m9iA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		5 / 12 ALA A  97
PRO A  69
THR A 138
GLY A 182
THR A 179
 None
 1.39A 5hfjG-3m9iA:
undetectable		 5hfjG-3m9iA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		5 / 10 VAL A 164
THR A 148
ILE A 145
TYR A  89
GLY A  60
 None
 1.13A 5mxbA-3m9iA:
undetectable		 5mxbA-3m9iA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3m9i LENS FIBER MAJOR
INTRINSIC PROTEIN
(Ovis
aries) 		4 / 5 PRO A  69
GLU A  16
ARG A  85
THR A  72
 None
 1.43A 5uxcA-3m9iA:
undetectable		 5uxcA-3m9iA:
23.08