SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 7 GLN A  34
LEU A 122
SER A  42
ASN A 106
 None
None
GOL  A 310 (-3.4A)
None
 1.26A 1ig3A-3m9uA:
undetectable
1ig3B-3m9uA:
undetectable		 1ig3A-3m9uA:
22.12
1ig3B-3m9uA:
22.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
ARG A 100
THR A 184
GLN A 221
ASP A 224
 None
 0.94A 1rqjA-3m9uA:
34.4		 1rqjA-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
ARG A 100
THR A 184
ASP A 224
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.80A 1rqjA-3m9uA:
34.4		 1rqjA-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 11 SER A  85
LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 1.09A 1rqjA-3m9uA:
34.4		 1rqjA-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 11 SER A  85
LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 1.23A 1rqjA-3m9uA:
34.4		 1rqjA-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
ASP A  95
ARG A 100
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.48A 1rqjA-3m9uA:
34.4		 1rqjA-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
ASP A  95
LYS A 183
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.74A 1rqjA-3m9uA:
34.4		 1rqjA-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
LYS A 183
THR A 184
ASP A 224
 None
GOL  A 310 ( 4.3A)
None
None
None
 1.00A 1rqjA-3m9uA:
34.4		 1rqjA-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 11 SER A  85
LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 0.91A 1rqjB-3m9uA:
34.3		 1rqjB-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
ASP A  89
ARG A 100
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.77A 1rqjB-3m9uA:
34.3		 1rqjB-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
ASP A  89
LYS A 183
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.97A 1rqjB-3m9uA:
34.3		 1rqjB-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
ASP A  95
ARG A 100
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.46A 1rqjB-3m9uA:
34.3		 1rqjB-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
ASP A  95
LYS A 183
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.72A 1rqjB-3m9uA:
34.3		 1rqjB-3m9uA:
42.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 SER A  85
LEU A  86
LYS A 183
THR A 184
ASP A 224
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.99A 1rqjB-3m9uA:
34.3		 1rqjB-3m9uA:
42.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.86A 1yhlA-3m9uA:
25.0		 1yhlA-3m9uA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 LEU A  86
ASP A  89
ASP A  95
ARG A 100
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.91A 1yq7A-3m9uA:
24.9		 1yq7A-3m9uA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.92A 1yv5A-3m9uA:
25.0		 1yv5A-3m9uA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ASP A  95
ARG A 100
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.76A 1yv5A-3m9uA:
25.0		 1yv5A-3m9uA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ASP A  95
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.94A 1yv5A-3m9uA:
25.0		 1yv5A-3m9uA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 6 HIS A 107
ASN A  96
THR A 105
PRO A 104
 None
None
GOL  A 310 (-4.3A)
None
 1.50A 2ez7A-3m9uA:
undetectable		 2ez7A-3m9uA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.93A 2f8cF-3m9uA:
26.0		 2f8cF-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.11A 2f8cF-3m9uA:
26.0		 2f8cF-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.31A 2f8cF-3m9uA:
26.0		 2f8cF-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.96A 2f8zF-3m9uA:
26.0		 2f8zF-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.10A 2f8zF-3m9uA:
26.0		 2f8zF-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.27A 2f8zF-3m9uA:
26.0		 2f8zF-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 12 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.88A 2f94F-3m9uA:
25.7		 2f94F-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.12A 2f9kF-3m9uA:
25.8		 2f9kF-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.31A 2f9kF-3m9uA:
25.8		 2f9kF-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 9 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.14A 2o1oA-3m9uA:
24.1		 2o1oA-3m9uA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 9 LEU A  86
ASP A  89
ASP A  95
ARG A 100
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
None
 0.96A 2o1oA-3m9uA:
24.1		 2o1oA-3m9uA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.14A 2o1oB-3m9uA:
25.4		 2o1oB-3m9uA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ASP A  95
ARG A 100
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.92A 2o1oB-3m9uA:
25.4		 2o1oB-3m9uA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ASP A  95
ARG A 100
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.07A 2q58A-3m9uA:
14.6		 2q58A-3m9uA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 12 LEU A 143
ALA A 146
ALA A 194
LEU A  78
LEU A 187
 None
 0.93A 2yqzA-3m9uA:
undetectable		 2yqzA-3m9uA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		3 / 3 MET A  94
GLU A 246
ASP A 225
 None
 1.08A 3a25A-3m9uA:
undetectable		 3a25A-3m9uA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.90A 3ez3D-3m9uA:
24.4		 3ez3D-3m9uA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ASP A  95
ARG A 100
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.82A 3ez3D-3m9uA:
24.4		 3ez3D-3m9uA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ASP A  95
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.04A 3ez3D-3m9uA:
24.4		 3ez3D-3m9uA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		3 / 3 SER A 270
ASP A 266
ASP A 214
 GOL  A 312 (-3.6A)
GOL  A 312 (-2.9A)
None
 0.66A 3iv6A-3m9uA:
undetectable		 3iv6A-3m9uA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		3 / 3 SER A 270
ASP A 266
ASP A 214
 GOL  A 312 (-3.6A)
GOL  A 312 (-2.9A)
None
 0.64A 3iv6C-3m9uA:
undetectable		 3iv6C-3m9uA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ASP A  95
ARG A 100
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.79A 3n46F-3m9uA:
25.7		 3n46F-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ASP A  95
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.01A 3n46F-3m9uA:
25.7		 3n46F-3m9uA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 7 SER A  30
VAL A  43
ILE A  26
THR A 124
 None
 1.02A 3tneB-3m9uA:
undetectable		 3tneB-3m9uA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 7 PHE A 216
PHE A 212
ALA A 191
LEU A 287
 None
 1.09A 4ejgA-3m9uA:
undetectable		 4ejgA-3m9uA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 8 PRO A  52
VAL A  75
PRO A  68
GLN A  13
 None
 1.04A 4iilA-3m9uA:
undetectable		 4iilA-3m9uA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 9 LEU A  86
ASP A  89
ARG A 100
GLN A 160
LYS A 183
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.24A 4kfaA-3m9uA:
25.2		 4kfaA-3m9uA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.91A 4kpdA-3m9uA:
26.0		 4kpdA-3m9uA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.11A 4kpdA-3m9uA:
26.0		 4kpdA-3m9uA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.27A 4kpdA-3m9uA:
26.0		 4kpdA-3m9uA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.08A 4kq5A-3m9uA:
25.3		 4kq5A-3m9uA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.27A 4kq5A-3m9uA:
25.3		 4kq5A-3m9uA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.92A 4kqsA-3m9uA:
25.7		 4kqsA-3m9uA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 12 MET A  76
VAL A  75
LEU A  18
ALA A  57
LEU A  50
 None
 1.29A 4m11C-3m9uA:
undetectable		 4m11C-3m9uA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 12 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.94A 4ng6A-3m9uA:
25.5		 4ng6A-3m9uA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 12 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.13A 4ng6A-3m9uA:
25.5		 4ng6A-3m9uA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.90A 4nkeA-3m9uA:
25.5		 4nkeA-3m9uA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 9 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.84A 4nkfA-3m9uA:
25.7		 4nkfA-3m9uA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.90A 4nuaA-3m9uA:
25.8		 4nuaA-3m9uA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 9 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.91A 4oguA-3m9uA:
25.7		 4oguA-3m9uA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 9 LEU A  86
ASP A  89
ASP A  95
ARG A 100
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.80A 4oguA-3m9uA:
25.7		 4oguA-3m9uA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 9 LEU A  86
ASP A  89
ASP A  95
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.04A 4oguA-3m9uA:
25.7		 4oguA-3m9uA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 11 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.10A 4p0wA-3m9uA:
25.8		 4p0wA-3m9uA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.91A 4rxdA-3m9uA:
24.1		 4rxdA-3m9uA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.89A 4rxdB-3m9uA:
24.4		 4rxdB-3m9uA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.10A 4rxdB-3m9uA:
24.4		 4rxdB-3m9uA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.26A 4rxdB-3m9uA:
24.4		 4rxdB-3m9uA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.90A 4rxdC-3m9uA:
24.5		 4rxdC-3m9uA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.11A 4rxdC-3m9uA:
24.5		 4rxdC-3m9uA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.26A 4rxdC-3m9uA:
24.5		 4rxdC-3m9uA:
22.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 8 SER A  85
LEU A  86
ASP A  89
ARG A 100
GLN A 160
 None
GOL  A 310 ( 4.3A)
None
None
None
 1.20A 4umjA-3m9uA:
33.8		 4umjA-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 8 SER A  85
LEU A  86
ASP A  89
GLN A 160
LYS A 183
 None
GOL  A 310 ( 4.3A)
None
None
None
 1.47A 4umjA-3m9uA:
33.8		 4umjA-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 8 SER A  85
LEU A  86
ASP A  95
ARG A 100
MET A 156
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.40A 4umjA-3m9uA:
33.8		 4umjA-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 8 SER A  85
LEU A  86
ASP A  95
MET A 156
LYS A 183
 None
GOL  A 310 ( 4.3A)
None
None
None
 0.80A 4umjA-3m9uA:
33.8		 4umjA-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 9 SER A  85
LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 1.12A 4umjB-3m9uA:
34.9		 4umjB-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 9 SER A  85
LEU A  86
ASP A  89
ASP A  95
ARG A 100
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 0.71A 4umjB-3m9uA:
34.9		 4umjB-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 9 SER A  85
LEU A  86
ASP A  89
ASP A  95
LYS A 183
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 0.93A 4umjB-3m9uA:
34.9		 4umjB-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 9 SER A  85
LEU A  86
ASP A  89
GLN A 160
LYS A 183
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 1.29A 4umjB-3m9uA:
34.9		 4umjB-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 9 SER A  85
LEU A  86
ASP A  95
ARG A 100
MET A 156
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 0.42A 4umjB-3m9uA:
34.9		 4umjB-3m9uA:
44.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		6 / 9 SER A  85
LEU A  86
ASP A  95
MET A 156
LYS A 183
THR A 184
 None
GOL  A 310 ( 4.3A)
None
None
None
None
 0.71A 4umjB-3m9uA:
34.9		 4umjB-3m9uA:
44.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 6 HIS A  82
GLY A  47
GLU A  79
ARG A  49
 None
 0.95A 4zbqA-3m9uA:
undetectable		 4zbqA-3m9uA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 12 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.90A 5cg5A-3m9uA:
25.1		 5cg5A-3m9uA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 12 LEU A  86
ARG A 100
THR A 184
GLN A 221
ASP A 224
 GOL  A 310 ( 4.3A)
None
None
None
None
 0.93A 5cg6A-3m9uA:
25.8		 5cg6A-3m9uA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 12 LEU A  86
ASP A  89
ARG A 100
GLN A 160
THR A 184
 GOL  A 310 ( 4.3A)
None
None
None
None
 1.12A 5cg6A-3m9uA:
25.8		 5cg6A-3m9uA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		5 / 10 ASP A  89
ASP A 163
GLN A 221
ASP A 224
ASP A 225
 None
 1.38A 5eroC-3m9uA:
23.4		 5eroC-3m9uA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 8 THR A  55
GLN A 193
ILE A 197
GLY A 195
 None
 0.87A 5nzxA-3m9uA:
undetectable		 5nzxA-3m9uA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 7 THR A  55
GLN A 193
ILE A 197
GLY A 195
 None
 0.94A 5nzyA-3m9uA:
undetectable		 5nzyA-3m9uA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 6 VAL A  43
LEU A 122
LEU A 125
LEU A  35
 None
 1.07A 6f6sA-3m9uA:
undetectable
6f6sB-3m9uA:
undetectable		 6f6sA-3m9uA:
14.05
6f6sB-3m9uA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 7 LEU A  86
ASP A  89
ARG A 100
GLN A 160
 GOL  A 310 ( 4.3A)
None
None
None
 1.15A 6g31D-3m9uA:
21.7		 6g31D-3m9uA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3m9u FARNESYL-DIPHOSPHATE
SYNTHASE
(Lactobacillus
brevis) 		4 / 6 LEU A  86
ASP A  89
ARG A 100
GLN A 160
 GOL  A 310 ( 4.3A)
None
None
None
 1.18A 6g31J-3m9uA:
22.8		 6g31J-3m9uA:
11.58