SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 8 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.99A 1dz9A-3m9vA:
undetectable		 1dz9A-3m9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 8 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.98A 1o76B-3m9vA:
undetectable		 1o76B-3m9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 12 ALA A 173
LEU A  29
GLY A 176
PHE A 179
LEU A  57
 None
 1.22A 1qabF-3m9vA:
undetectable		 1qabF-3m9vA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 12 LEU A  86
ALA A  88
LEU A  14
GLY A  22
LEU A  25
 None
 0.95A 1qknA-3m9vA:
undetectable		 1qknA-3m9vA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.97A 1t85A-3m9vA:
undetectable		 1t85A-3m9vA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.03A 1t87A-3m9vA:
undetectable		 1t87A-3m9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 6 LEU A 371
ALA A 276
LEU A 357
SER A 358
 None
 1.06A 1tz8C-3m9vA:
undetectable
1tz8D-3m9vA:
undetectable		 1tz8C-3m9vA:
14.82
1tz8D-3m9vA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 THR A  51
PRO A  50
THR A  53
 None
 0.85A 1unmE-3m9vA:
undetectable		 1unmE-3m9vA:
5.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 8 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.99A 1uyuA-3m9vA:
undetectable		 1uyuA-3m9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 8 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.99A 1uyuB-3m9vA:
undetectable		 1uyuB-3m9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 ILE A  36
PHE A  54
LEU A  57
ASP A  93
 None
 0.70A 1yc2E-3m9vA:
undetectable		 1yc2E-3m9vA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.99A 1yrcA-3m9vA:
undetectable		 1yrcA-3m9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.03A 1yrdA-3m9vA:
undetectable		 1yrdA-3m9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 THR A  53
THR A  51
PRO A  50
 None
 0.83A 209dC-3m9vA:
undetectable		 209dC-3m9vA:
5.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 10 LEU A  57
LEU A  29
LEU A  33
ILE A  36
ALA A  97
 None
 1.04A 2bxeB-3m9vA:
undetectable		 2bxeB-3m9vA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 6 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.96A 2feuA-3m9vA:
undetectable		 2feuA-3m9vA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.96A 2feuB-3m9vA:
undetectable		 2feuB-3m9vA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 12 ALA A  88
LEU A  14
ARG A 306
GLY A  22
LEU A  25
 None
 1.04A 2jfaB-3m9vA:
undetectable		 2jfaB-3m9vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 9 LEU A  62
PHE A  54
THR A  96
VAL A  89
LEU A  57
 None
 1.17A 2m9qA-3m9vA:
undetectable		 2m9qA-3m9vA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 LEU A 371
PRO A 370
LEU A 374
 None
 0.48A 2po7B-3m9vA:
undetectable		 2po7B-3m9vA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 6 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.04A 2zuiA-3m9vA:
undetectable		 2zuiA-3m9vA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.02A 2zwtA-3m9vA:
undetectable		 2zwtA-3m9vA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.02A 2zwuA-3m9vA:
undetectable		 2zwuA-3m9vA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 THR A  51
PRO A  50
THR A  53
 None
 0.68A 316dC-3m9vA:
undetectable		 316dC-3m9vA:
5.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.93A 3fwfA-3m9vA:
undetectable		 3fwfA-3m9vA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.97A 3fwfB-3m9vA:
undetectable		 3fwfB-3m9vA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.03A 3fwiA-3m9vA:
undetectable		 3fwiA-3m9vA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.97A 3fwjA-3m9vA:
undetectable		 3fwjA-3m9vA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 LEU A 371
PRO A 370
LEU A 374
 None
 0.51A 3hcrA-3m9vA:
undetectable		 3hcrA-3m9vA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.94A 3l63A-3m9vA:
undetectable		 3l63A-3m9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 11 ALA A  88
LEU A  14
ARG A 306
GLY A  22
LEU A  25
 None
 1.22A 3uudA-3m9vA:
undetectable		 3uudA-3m9vA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.98A 3wrhA-3m9vA:
undetectable		 3wrhA-3m9vA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.00A 3wrjA-3m9vA:
undetectable		 3wrjA-3m9vA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.98A 3wrlA-3m9vA:
undetectable		 3wrlA-3m9vA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.96A 3wrlE-3m9vA:
undetectable		 3wrlE-3m9vA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.00A 3wrmA-3m9vA:
undetectable		 3wrmA-3m9vA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.97A 3wrmF-3m9vA:
undetectable		 3wrmF-3m9vA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 THR A  51
PRO A  50
THR A  53
 None
 0.83A 4hivD-3m9vA:
undetectable		 4hivD-3m9vA:
5.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 12 LEU A 108
ASP A  77
ALA A 318
LEU A  26
THR A  19
 None
 1.36A 4iarA-3m9vA:
3.7		 4iarA-3m9vA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 8 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.99A 4l4eA-3m9vA:
undetectable		 4l4eA-3m9vA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 8 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 1.01A 4l4fA-3m9vA:
undetectable		 4l4fA-3m9vA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.99A 4l4gA-3m9vA:
undetectable		 4l4gA-3m9vA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 10 LEU A 313
LEU A 262
ALA A  83
LEU A 305
LEU A  14
 None
 1.28A 4p65A-3m9vA:
undetectable
4p65B-3m9vA:
undetectable
4p65F-3m9vA:
undetectable
4p65H-3m9vA:
undetectable		 4p65A-3m9vA:
3.55
4p65B-3m9vA:
10.26
4p65F-3m9vA:
10.26
4p65H-3m9vA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 10 GLY A 253
ALA A 316
ASP A 317
SER A 320
ALA A 321
 TYD  A 901 (-3.3A)
None
None
None
None
 0.85A 4wnuD-3m9vA:
undetectable		 4wnuD-3m9vA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WZM_A_ACTA503_0
(RNA DEPENDENT RNA
POLYMERASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 4 ASP A 377
ASP A  93
ASP A  44
ALA A  94
 None
 1.42A 4wzmA-3m9vA:
0.9		 4wzmA-3m9vA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 12 MET A 327
GLU A 113
LEU A  79
THR A  66
GLY A 107
 None
TYD  A 901 (-3.8A)
None
None
None
 1.33A 4zjlA-3m9vA:
undetectable		 4zjlA-3m9vA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 12 THR A  53
PHE A  54
LEU A  57
ILE A 128
VAL A 264
 None
 1.35A 5dlvB-3m9vA:
undetectable		 5dlvB-3m9vA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 11 ALA A  88
LEU A  14
ARG A 306
GLY A  22
LEU A  25
 None
 1.21A 5dxbB-3m9vA:
undetectable		 5dxbB-3m9vA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 11 ALA A  88
LEU A  14
ARG A 306
GLY A  22
LEU A  25
 None
 1.25A 5dxgB-3m9vA:
undetectable		 5dxgB-3m9vA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 MET A 334
GLN A 333
ARG A 332
 None
 1.07A 5ewzB-3m9vA:
4.8		 5ewzB-3m9vA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 6 LEU A 371
ALA A 276
LEU A 357
SER A 358
 None
 1.06A 5l4iB-3m9vA:
undetectable		 5l4iB-3m9vA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 THR A  96
PRO A  50
ASP A  52
 None
 0.92A 5l8dB-3m9vA:
undetectable		 5l8dB-3m9vA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 12 LEU A  74
ALA A  21
PRO A  17
LEU A  14
LEU A 313
 None
 1.11A 5ljeA-3m9vA:
undetectable		 5ljeA-3m9vA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 MET A 334
GLN A 333
ARG A 332
 None
 1.11A 5m35B-3m9vA:
4.5		 5m35B-3m9vA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 THR A  96
PRO A  50
ASP A  52
 None
 0.92A 5mwuB-3m9vA:
undetectable		 5mwuB-3m9vA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 7 THR A 151
LEU A 163
VAL A 199
VAL A 170
 None
 0.90A 5wk9A-3m9vA:
undetectable		 5wk9A-3m9vA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 MET A 334
GLN A 333
ARG A 332
 None
 1.13A 6fn9A-3m9vA:
undetectable		 6fn9A-3m9vA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 MET A 334
GLN A 333
ARG A 332
 None
 1.14A 6fnaB-3m9vA:
undetectable		 6fnaB-3m9vA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		3 / 3 MET A 334
GLN A 333
ARG A 332
 None
 1.13A 6fnbA-3m9vA:
undetectable		 6fnbA-3m9vA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		4 / 5 LEU A 104
THR A  66
THR A 109
GLY A 107
 None
None
TYD  A 901 (-4.0A)
None
 1.25A 6gtqA-3m9vA:
undetectable		 6gtqA-3m9vA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3m9v FAD-DEPENDENT
OXIDOREDUCTASE
(Actinomadura
kijaniata) 		5 / 12 VAL A 345
HIS A 101
VAL A 264
PHE A 338
MET A 335
 None
 1.41A 6j21A-3m9vA:
3.5		 6j21A-3m9vA:
21.66