SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 131
ALA A 174
GLY A 220
ALA A 203
ILE A 218
 None
 1.01A 1gtnL-3m9xA:
undetectable
1gtnV-3m9xA:
undetectable		 1gtnL-3m9xA:
12.87
1gtnV-3m9xA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 220
ALA A 203
ILE A 218
GLY A 131
ALA A 174
 None
 1.02A 1utdO-3m9xA:
undetectable
1utdP-3m9xA:
undetectable		 1utdO-3m9xA:
12.87
1utdP-3m9xA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 11 GLY A 220
ALA A 203
ILE A 218
GLY A 131
ALA A 174
 None
 1.03A 1utdP-3m9xA:
undetectable
1utdQ-3m9xA:
undetectable		 1utdP-3m9xA:
12.87
1utdQ-3m9xA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		6 / 12 GLY A 201
ALA A 200
ASP A 197
ILE A 231
VAL A 216
ILE A 218
 None
 1.38A 3d1xA-3m9xA:
undetectable		 3d1xA-3m9xA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 ILE A   5
VAL A  61
LYS A  85
PHE A 100
PRO A 264
 None
 1.16A 3em0B-3m9xA:
undetectable		 3em0B-3m9xA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 GLY A 259
VAL A   3
ILE A 254
GLN A 262
 None
 0.90A 3fi0E-3m9xA:
undetectable		 3fi0E-3m9xA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 GLY A 259
VAL A   3
ILE A 254
GLN A 262
 None
 0.85A 3fi0P-3m9xA:
undetectable		 3fi0P-3m9xA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 ALA A 194
VAL A 193
GLN A 145
 None
 0.60A 3of4B-3m9xA:
undetectable		 3of4B-3m9xA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 8 ALA A  79
LEU A  62
ASP A  99
ASP A  97
 None
 1.01A 3qj7A-3m9xA:
undetectable
3qj7D-3m9xA:
undetectable		 3qj7A-3m9xA:
22.04
3qj7D-3m9xA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 ASP A  10
TYR A  67
TRP A  17
 None
 1.21A 4p7nA-3m9xA:
undetectable		 4p7nA-3m9xA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 ASP A 197
LYS A 229
LEU A 307
 None
 0.78A 4ptjA-3m9xA:
2.1		 4ptjA-3m9xA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 TYR A  89
SER A 103
TRP A  17
 None
 0.95A 5n8jB-3m9xA:
undetectable		 5n8jB-3m9xA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 TYR A  89
SER A 103
TRP A  17
 None
 0.98A 5n8jA-3m9xA:
undetectable		 5n8jA-3m9xA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3m9x D-XYLOSE-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 TYR A  89
SER A 103
TRP A  17
 None
 1.02A 5n8jD-3m9xA:
undetectable		 5n8jD-3m9xA:
21.97