SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ma2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 3ma2 METALLOPROTEINASE
INHIBITOR 1
(Homo
sapiens) 		5 / 12 TYR B 372
TYR B 362
LEU B 394
LEU B 393
ILE B 358
 None
 1.38A 1fmlA-3ma2B:
undetectable		 1fmlA-3ma2B:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3ma2 METALLOPROTEINASE
INHIBITOR 1
(Homo
sapiens) 		5 / 12 ASN B 406
GLU B 381
GLU B 382
VAL B 361
ILE B 385
 None
 1.43A 3jayA-3ma2B:
undetectable		 3jayA-3ma2B:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 3ma2 METALLOPROTEINASE
INHIBITOR 1
(Homo
sapiens) 		4 / 5 PHE B 323
ILE B 340
GLY B 325
HIS B 374
 None
 1.34A 3r0lD-3ma2B:
undetectable		 3r0lD-3ma2B:
24.66