SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DG5_A_TOPA201_1
(DIHYDROFOLATE
REDUCTASE)		 3mah ASPARTOKINASE
(Porphyromonas
gingivalis) 		5 / 11 ILE A 361
ALA A 364
ILE A 368
PHE A 331
ILE A 310
 None
 1.12A 1dg5A-3mahA:
undetectable		 1dg5A-3mahA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3mah ASPARTOKINASE
(Porphyromonas
gingivalis) 		5 / 12 VAL A 338
THR A 308
LYS A 375
VAL A 348
LEU A 327
 None
 1.19A 2jn3A-3mahA:
undetectable		 2jn3A-3mahA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 3mah ASPARTOKINASE
(Porphyromonas
gingivalis) 		6 / 10 LEU A 401
VAL A 404
GLY A 403
LEU A 434
SER A 435
ALA A 430
 None
 1.35A 2v3kA-3mahA:
undetectable		 2v3kA-3mahA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3mah ASPARTOKINASE
(Porphyromonas
gingivalis) 		4 / 7 GLY A 403
ALA A 430
ALA A 433
VAL A 422
 None
 0.79A 3a2qA-3mahA:
undetectable		 3a2qA-3mahA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 3mah ASPARTOKINASE
(Porphyromonas
gingivalis) 		3 / 3 SER A 320
MET A 324
ASP A 370
 None
 0.97A 4mm4B-3mahA:
undetectable		 4mm4B-3mahA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3mah ASPARTOKINASE
(Porphyromonas
gingivalis) 		5 / 11 LEU A 358
GLY A 306
ILE A 352
ASN A 354
VAL A 309
 None
 1.23A 5hjiA-3mahA:
3.4		 5hjiA-3mahA:
16.47