SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3maz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)
3maz SIGNAL-TRANSDUCING
ADAPTOR PROTEIN 1

(Homo
sapiens)
3 / 3 ASN A 199
ARG A 216
ASP A 220
None
0.98A 2qe6A-3mazA:
undetectable
2qe6A-3mazA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)
3maz SIGNAL-TRANSDUCING
ADAPTOR PROTEIN 1

(Homo
sapiens)
3 / 3 ASN A 199
ARG A 216
ASP A 220
None
0.93A 2qe6B-3mazA:
undetectable
2qe6B-3mazA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
3maz SIGNAL-TRANSDUCING
ADAPTOR PROTEIN 1

(Homo
sapiens)
4 / 5 THR A 214
SER A 212
SER A 206
ARG A 184
None
1.39A 3hlwB-3mazA:
undetectable
3hlwB-3mazA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)
3maz SIGNAL-TRANSDUCING
ADAPTOR PROTEIN 1

(Homo
sapiens)
4 / 6 THR A 260
ASN A 263
ILE A 219
GLU A 218
None
1.26A 5uigA-3mazA:
undetectable
5uigA-3mazA:
15.29