SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mb2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)
3mb2 4-OXALOCROTONATE
TAUTOMERASE FAMILY
ENZYME - BETA
SUBUNIT

(Chloroflexus
aurantiacus)
4 / 8 ALA B  20
PHE B  21
ALA B  25
LEU B   3
None
0.68A 2bxmA-3mb2B:
undetectable
2bxmA-3mb2B:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)
3mb2 4-OXALOCROTONATE
TAUTOMERASE FAMILY
ENZYME - ALPHA
SUBUNIT

(Chloroflexus
aurantiacus)
4 / 6 LEU A  41
LEU A   4
ILE A  43
ARG A   5
None
0.95A 2rlfC-3mb2A:
undetectable
2rlfD-3mb2A:
undetectable
2rlfC-3mb2A:
18.18
2rlfD-3mb2A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)
3mb2 4-OXALOCROTONATE
TAUTOMERASE FAMILY
ENZYME - BETA
SUBUNIT

(Chloroflexus
aurantiacus)
5 / 12 LEU B   3
ILE B  33
GLY B  34
LEU B  42
ALA B  25
None
1.13A 5h5fA-3mb2B:
undetectable
5h5fA-3mb2B:
13.68