SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mbe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 8 PHE B 122
THR B 145
VAL B 129
ILE B 127
 None
 0.71A 2qbmA-3mbeB:
undetectable		 2qbmA-3mbeB:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 6 LEU B  26
ALA B  78
LEU B  75
THR B  77
 None
 1.08A 2roxB-3mbeB:
2.7		 2roxB-3mbeB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		4 / 6 ASP C  93
ILE C  91
LEU C  79
GLU C  97
 None
 1.04A 2ya7A-3mbeC:
undetectable		 2ya7A-3mbeC:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		4 / 6 ASP C  93
ILE C  91
LEU C  79
GLU C  97
 None
 1.03A 2ya7B-3mbeC:
undetectable		 2ya7B-3mbeC:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		4 / 6 ASP C  93
ILE C  91
LEU C  79
GLU C  97
 None
 1.04A 2ya7D-3mbeC:
undetectable		 2ya7D-3mbeC:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		3 / 3 PRO B 124
LEU B  94
ARG B  93
 None
 0.77A 3aqiB-3mbeB:
undetectable		 3aqiB-3mbeB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 5 VAL B  88
THR B  21
THR B  90
ARG B  93
 None
 1.18A 3bjwG-3mbeB:
undetectable		 3bjwG-3mbeB:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		4 / 7 SER C  84
LEU B  26
ALA B  78
LEU B  75
 None
 1.00A 3cfqA-3mbeC:
4.2
3cfqB-3mbeC:
4.4		 3cfqA-3mbeC:
17.54
3cfqB-3mbeC:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 7 LEU B  26
ALA B  78
LEU B  75
THR B  77
 None
 1.04A 3ozkB-3mbeB:
undetectable		 3ozkB-3mbeB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 6 LEU B  26
ALA B  78
LEU B  75
THR B  77
 None
 1.03A 4ikiB-3mbeB:
2.6		 4ikiB-3mbeB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 7 LEU B  26
ALA B  78
LEU B  75
THR B  77
 None
 1.01A 4ikjA-3mbeB:
undetectable
4ikjB-3mbeB:
2.6		 4ikjA-3mbeB:
17.62
4ikjB-3mbeB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 7 LEU B  26
ALA B  78
LEU B  75
THR B  77
 None
 1.02A 4ikkA-3mbeB:
2.6
4ikkB-3mbeB:
2.6		 4ikkA-3mbeB:
17.62
4ikkB-3mbeB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		4 / 7 SER C  84
LEU B  26
ALA B  78
LEU B  75
 None
 1.02A 4ikkA-3mbeC:
4.2
4ikkB-3mbeC:
3.6		 4ikkA-3mbeC:
18.31
4ikkB-3mbeC:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 4 VAL B 140
THR B 139
GLU B 138
GLU B 137
 None
 1.32A 4l78A-3mbeB:
undetectable		 4l78A-3mbeB:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 3mbe MHC CLASS II H2-IAG7
BETA CHAIN
(Mus
musculus) 		4 / 7 ARG B  25
VAL B  27
GLU B  14
ARG B  29
 None
 1.29A 4mv7A-3mbeB:
undetectable		 4mv7A-3mbeB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  88
SER C  87
TYR C  86
 None
 0.84A 5jsdA-3mbeC:
2.1		 5jsdA-3mbeC:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  88
SER C  87
TYR C  86
 None
 0.85A 5jsdB-3mbeC:
2.6		 5jsdB-3mbeC:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  88
SER C  87
TYR C  86
 None
 0.84A 5jsdC-3mbeC:
undetectable		 5jsdC-3mbeC:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  88
SER C  87
TYR C  86
 None
 0.84A 5jseA-3mbeC:
2.2		 5jseA-3mbeC:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  88
SER C  87
TYR C  86
 None
 0.83A 5jseB-3mbeC:
undetectable		 5jseB-3mbeC:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		3 / 3 THR C  88
SER C  87
TYR C  86
 None
 0.83A 5jseC-3mbeC:
undetectable		 5jseC-3mbeC:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		4 / 5 ILE C 191
THR C 173
THR C 154
LEU C 178
 None
 1.13A 6f3mD-3mbeC:
undetectable		 6f3mD-3mbeC:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3mbe TCR 21.3 ALPHA CHAIN
(Mus
musculus) 		3 / 3 ASP C 179
LEU C  96
ARG C  78
 None
 0.79A 7dfrA-3mbeC:
undetectable		 7dfrA-3mbeC:
20.35