SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mbf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		4 / 5 LEU A  72
GLY A  23
ALA A  27
ILE A  71
 None
None
None
2FP  A 345 ( 4.7A)
 0.84A 2aohB-3mbfA:
undetectable		 2aohB-3mbfA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 LEU A 245
ASN A 279
ARG A 285
 None
 0.84A 2qhfA-3mbfA:
undetectable		 2qhfA-3mbfA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		4 / 8 ALA A 271
SER A 290
GLY A  23
ALA A 326
 None
 0.85A 2vh3B-3mbfA:
undetectable		 2vh3B-3mbfA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 PHE A 136
SER A 292
LEU A  25
 None
2FP  A 345 (-4.4A)
None
 0.69A 2w1bA-3mbfA:
undetectable		 2w1bA-3mbfA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		5 / 9 ALA A 271
ASP A 270
TYR A 224
PRO A 237
VAL A 240
 None
 1.47A 2x08A-3mbfA:
0.0		 2x08A-3mbfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		5 / 12 TYR A 146
ILE A 115
ILE A 200
LEU A 142
VAL A 117
 None
 1.24A 3fpjB-3mbfA:
undetectable		 3fpjB-3mbfA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		5 / 12 GLY A 217
GLN A 170
VAL A 175
MET A 205
ILE A  17
 None
 1.24A 3h52B-3mbfA:
undetectable		 3h52B-3mbfA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		4 / 7 GLY A 258
PHE A 274
PHE A 261
PHE A 293
 None
 1.14A 3ko0L-3mbfA:
undetectable
3ko0N-3mbfA:
undetectable		 3ko0L-3mbfA:
16.02
3ko0N-3mbfA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		4 / 7 PHE A 261
PHE A 293
GLY A 258
PHE A 274
 None
 1.12A 3ko0R-3mbfA:
undetectable
3ko0T-3mbfA:
undetectable		 3ko0R-3mbfA:
16.02
3ko0T-3mbfA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		5 / 9 PRO A 176
MET A 205
VAL A 213
ILE A 256
ILE A 215
 None
 1.27A 3p4wB-3mbfA:
1.3		 3p4wB-3mbfA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		5 / 12 GLY A 267
ASP A 299
ARG A  54
ALA A 294
ALA A  26
 None
None
None
2FP  A 345 (-3.5A)
2FP  A 345 (-3.4A)
 1.19A 3sueB-3mbfA:
undetectable		 3sueB-3mbfA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		4 / 8 ASN A  73
GLU A  78
GLU A  75
GLU A  47
 None
 1.14A 4mj8B-3mbfA:
1.1
4mj8C-3mbfA:
undetectable		 4mj8B-3mbfA:
21.35
4mj8C-3mbfA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 THR A 226
SER A 227
TYR A 188
 None
 0.76A 5jsdA-3mbfA:
undetectable		 5jsdA-3mbfA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 THR A 226
SER A 227
TYR A 188
 None
 0.76A 5jsdB-3mbfA:
undetectable		 5jsdB-3mbfA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 THR A 226
SER A 227
TYR A 188
 None
 0.75A 5jsdC-3mbfA:
undetectable		 5jsdC-3mbfA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 THR A 226
SER A 227
TYR A 188
 None
 0.76A 5jseA-3mbfA:
undetectable		 5jseA-3mbfA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 THR A 226
SER A 227
TYR A 188
 None
 0.76A 5jseB-3mbfA:
undetectable		 5jseB-3mbfA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 THR A 226
SER A 227
TYR A 188
 None
 0.76A 5jseC-3mbfA:
undetectable		 5jseC-3mbfA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		4 / 8 ILE A 177
PHE A 291
LEU A 297
ALA A 294
 None
None
None
2FP  A 345 (-3.5A)
 0.87A 5y7pC-3mbfA:
undetectable		 5y7pC-3mbfA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 ARG A  36
LYS A  32
ARG A 125
 None
 1.19A 6c06D-3mbfA:
0.0		 6c06D-3mbfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		4 / 7 ALA A 166
ILE A 220
VAL A 218
PRO A 253
 None
 0.96A 6cduF-3mbfA:
undetectable
6cduJ-3mbfA:
undetectable		 6cduF-3mbfA:
22.52
6cduJ-3mbfA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 PHE A  53
ARG A  37
ALA A  26
 None
2FP  A 345 ( 4.9A)
2FP  A 345 (-3.4A)
 0.85A 6ecfB-3mbfA:
2.4		 6ecfB-3mbfA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Encephalitozoon
cuniculi) 		3 / 3 THR A 203
GLU A 113
ASN A 156
 None
 0.90A 6nj9K-3mbfA:
undetectable		 6nj9K-3mbfA:
22.90