SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mbr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		3 / 3 ALA X 216
VAL X 226
TRP X 246
 None
 0.87A 1jo3A-3mbrX:
undetectable		 1jo3A-3mbrX:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		3 / 3 ALA X 216
VAL X 226
TRP X 246
 None
 0.87A 1jo3B-3mbrX:
undetectable		 1jo3B-3mbrX:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		3 / 3 ALA X 216
VAL X 226
TRP X 246
 None
 0.96A 1nrmA-3mbrX:
undetectable		 1nrmA-3mbrX:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 VAL X 163
LEU X 170
TRP X 206
ALA X 185
LEU X 183
 None
 1.06A 2aylA-3mbrX:
undetectable		 2aylA-3mbrX:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 LEU X 176
ILE X 230
VAL X 203
VAL X 163
PRO X 198
 None
 0.96A 2ygpA-3mbrX:
undetectable		 2ygpA-3mbrX:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		4 / 6 LEU X 249
ASP X  70
LEU X  77
HIS X  53
 None
 1.00A 3bj8C-3mbrX:
undetectable
3bj8D-3mbrX:
undetectable		 3bj8C-3mbrX:
21.37
3bj8D-3mbrX:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		3 / 3 PRO X 256
LEU X 257
GLN X  28
 None
 0.48A 3hznG-3mbrX:
undetectable
3hznH-3mbrX:
undetectable		 3hznG-3mbrX:
21.32
3hznH-3mbrX:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		4 / 7 LEU X 173
VAL X 187
VAL X 163
LEU X 209
 None
 0.86A 3rgfA-3mbrX:
undetectable		 3rgfA-3mbrX:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		5 / 9 LEU X 227
LEU X 184
GLN X  28
TYR X  30
LEU X 212
 None
 1.12A 4ltwA-3mbrX:
undetectable		 4ltwA-3mbrX:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		5 / 11 LEU X  98
GLY X  88
GLN X 100
ALA X  80
SER X  65
 None
 1.38A 4wnuC-3mbrX:
undetectable		 4wnuC-3mbrX:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		3 / 3 LYS X 244
ARG X  79
VAL X  66
 None
 0.98A 4x3uA-3mbrX:
undetectable
4x3uB-3mbrX:
undetectable		 4x3uA-3mbrX:
12.97
4x3uB-3mbrX:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 VAL X 179
TYR X 139
ILE X  91
ILE X  99
TRP X  94
 None
 1.08A 4xucA-3mbrX:
undetectable		 4xucA-3mbrX:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 VAL X 179
TYR X 139
ILE X  91
ILE X  99
TRP X  94
 None
 1.03A 4xudA-3mbrX:
undetectable		 4xudA-3mbrX:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 VAL X 179
TYR X 139
ILE X  91
ILE X  99
TRP X  94
 None
 1.08A 4xueA-3mbrX:
undetectable		 4xueA-3mbrX:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		3 / 3 TYR X  86
THR X  61
THR X 102
 None
 0.78A 5aoxB-3mbrX:
undetectable		 5aoxB-3mbrX:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		4 / 5 ALA X  89
GLU X  45
ASN X 228
GLU X 175
 None
None
None
CA  X 300 (-2.9A)
 1.04A 5dwkC-3mbrX:
undetectable		 5dwkC-3mbrX:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 VAL X 163
LEU X 170
TRP X 206
ALA X 185
LEU X 183
 None
 1.05A 5ikrA-3mbrX:
undetectable		 5ikrA-3mbrX:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		4 / 7 TYR X 139
LEU X 131
VAL X  92
TRP X  94
 None
 1.09A 6g2pA-3mbrX:
undetectable		 6g2pA-3mbrX:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 3mbr GLUTAMINE
CYCLOTRANSFERASE
(Xanthomonas
campestris) 		4 / 7 GLY X 126
TYR X 124
ASN X 105
GLY X 108
 None
 0.87A 6n7fA-3mbrX:
undetectable		 6n7fA-3mbrX:
17.70