SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mbw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3mbw EPHRIN TYPE-A
RECEPTOR 2
EPHRIN-A1
(Homo
sapiens) 		4 / 7 ASN A  57
GLY B 117
THR B 115
SER A  68
 None
 1.17A 2o5yH-3mbwA:
undetectable
2o5yL-3mbwA:
undetectable		 2o5yH-3mbwA:
20.82
2o5yL-3mbwA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3mbw EPHRIN TYPE-A
RECEPTOR 2
EPHRIN-A1
(Homo
sapiens) 		5 / 10 LEU A 163
THR A 101
LEU B 116
GLY B 117
MET A  66
 None
 1.43A 3h9uD-3mbwA:
undetectable		 3h9uD-3mbwA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3mbw EPHRIN-A1
(Homo
sapiens) 		5 / 10 ILE B  39
VAL B 145
TYR B 127
ILE B  49
TRP B  25
 None
 1.38A 3uprA-3mbwB:
undetectable		 3uprA-3mbwB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3mbw EPHRIN-A1
(Homo
sapiens) 		5 / 10 ILE B  39
VAL B 145
TYR B 127
ILE B  49
TRP B  25
 None
 1.43A 3uprC-3mbwB:
undetectable		 3uprC-3mbwB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 3mbw EPHRIN TYPE-A
RECEPTOR 2
(Homo
sapiens) 		4 / 5 PHE A 156
SER A 154
ASN A 164
ASP A 148
 None
None
None
UNX  A 327 ( 2.7A)
 1.46A 5kpcA-3mbwA:
undetectable		 5kpcA-3mbwA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3mbw EPHRIN-A1
(Homo
sapiens) 		5 / 10 ILE B  39
VAL B 145
TYR B 127
ILE B  49
TRP B  25
 None
 1.39A 5u98A-3mbwB:
undetectable		 5u98A-3mbwB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3mbw EPHRIN-A1
(Homo
sapiens) 		5 / 10 ILE B  39
VAL B 145
TYR B 127
ILE B  49
TRP B  25
 None
 1.43A 5u98D-3mbwB:
undetectable		 5u98D-3mbwB:
18.93