SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mc1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 11 LEU A 193
ALA A 196
GLU A 192
ILE A 146
LEU A 174
 None
 1.21A 1g50A-3mc1A:
undetectable		 1g50A-3mc1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 ILE A 201
GLY A 182
GLY A 164
THR A 184
GLU A 207
 None
 0.98A 1nv8B-3mc1A:
2.6		 1nv8B-3mc1A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		3 / 3 ASP A 128
PHE A   7
ASN A   3
 None
 0.64A 1sg9B-3mc1A:
undetectable		 1sg9B-3mc1A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 10 GLY A  11
LEU A  13
ILE A  89
PHE A   7
LEU A 208
 NA  A 301 ( 4.3A)
None
None
None
None
 1.11A 2f8dB-3mc1A:
2.1		 2f8dB-3mc1A:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 ILE A  89
ILE A  20
ILE A 117
LEU A 118
THR A 107
 None
GOL  A 303 ( 4.6A)
None
None
None
 1.04A 2qo5A-3mc1A:
undetectable		 2qo5A-3mc1A:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 11 ILE A 130
ALA A 106
PHE A 127
THR A  14
ILE A  89
 None
 1.16A 2w3aA-3mc1A:
undetectable		 2w3aA-3mc1A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 ILE A 163
GLY A 164
ARG A 166
ASP A 165
PHE A   7
 None
None
None
NA  A 301 (-2.8A)
None
 1.06A 3jb1A-3mc1A:
undetectable		 3jb1A-3mc1A:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 182
GLY A 164
GLU A 192
ALA A 198
ASN A 199
 None
 0.93A 3kkzA-3mc1A:
undetectable		 3kkzA-3mc1A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 182
GLY A 164
GLU A 192
ALA A 198
ASN A 199
 None
 0.90A 3kkzB-3mc1A:
undetectable		 3kkzB-3mc1A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 164
ASP A   8
VAL A 170
GLY A 186
ILE A 201
 None
NA  A 301 (-3.1A)
None
None
None
 0.94A 3ku1C-3mc1A:
undetectable		 3ku1C-3mc1A:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 182
GLY A 164
GLU A 192
ALA A 198
ASN A 199
 None
 0.94A 3sxjA-3mc1A:
undetectable		 3sxjA-3mc1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 182
GLY A 164
GLU A 192
ALA A 198
ASN A 199
 None
 0.94A 3sxjB-3mc1A:
undetectable		 3sxjB-3mc1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 182
GLY A 164
GLU A 192
ALA A 198
ASN A 199
 None
 0.97A 3t7sA-3mc1A:
undetectable		 3t7sA-3mc1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 182
GLY A 164
GLU A 192
ALA A 198
ASN A 199
 None
 0.96A 3t7sB-3mc1A:
2.5		 3t7sB-3mc1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 182
GLY A 164
GLU A 192
ALA A 198
ASN A 199
 None
 0.92A 3t7sC-3mc1A:
undetectable		 3t7sC-3mc1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 182
GLY A 164
GLU A 192
ALA A 198
ASN A 199
 None
 0.92A 3t7sD-3mc1A:
undetectable		 3t7sD-3mc1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		4 / 7 THR A  21
GLY A  19
GLY A  11
THR A  12
 None
None
NA  A 301 ( 4.3A)
None
 0.77A 3tajA-3mc1A:
undetectable		 3tajA-3mc1A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 ASP A  37
VAL A  35
TYR A 168
SER A  52
LEU A  28
 None
 1.29A 4a84A-3mc1A:
undetectable		 4a84A-3mc1A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 LEU A 193
ALA A 196
GLU A 192
ILE A 146
LEU A 174
 None
 1.12A 4j24D-3mc1A:
undetectable		 4j24D-3mc1A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 ASP A  10
VAL A 105
ALA A 106
SER A 108
GLY A 132
 GOL  A 303 ( 3.8A)
None
None
None
None
 1.07A 4mm8A-3mc1A:
undetectable		 4mm8A-3mc1A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 10 ASP A  10
VAL A 105
ALA A 106
SER A 108
GLY A 132
 GOL  A 303 ( 3.8A)
None
None
None
None
 1.12A 4mmdA-3mc1A:
undetectable		 4mmdA-3mc1A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 ASP A  10
VAL A 105
ALA A 106
SER A 108
GLY A 132
 GOL  A 303 ( 3.8A)
None
None
None
None
 1.10A 4mmdB-3mc1A:
undetectable		 4mmdB-3mc1A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 12 GLY A 164
GLY A 182
THR A  12
ILE A  89
LEU A  93
 None
 1.00A 4n49A-3mc1A:
undetectable		 4n49A-3mc1A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 11 LEU A 193
ALA A 196
GLU A 192
ILE A 146
LEU A 174
 None
 1.22A 4pxmB-3mc1A:
undetectable		 4pxmB-3mc1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		4 / 5 VAL A 105
THR A 107
LEU A  93
VAL A 205
 None
 1.01A 6bqgA-3mc1A:
undetectable		 6bqgA-3mc1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 3mc1 PREDICTED
PHOSPHATASE, HAD
FAMILY
(Clostridium
acetobutylicum) 		5 / 10 LEU A 193
ALA A 196
GLU A 192
ILE A 146
LEU A 174
 None
 1.22A 6cbzB-3mc1A:
undetectable		 6cbzB-3mc1A:
17.12