SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3mc9 ALR2269 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 ASP A 282
VAL A 287
VAL A 223
LEU A 260
ALA A 278
 None
 1.41A 4yhaB-3mc9A:
undetectable		 4yhaB-3mc9A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3mc9 ALR2269 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 LEU A 235
THR A 236
PRO A 295
ILE A 332
 None
 0.98A 5fxtA-3mc9A:
undetectable		 5fxtA-3mc9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 3mc9 ALR2269 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 315
LEU A 316
VAL A 375
LEU A 373
LEU A 345
 None
 0.91A 6ajiA-3mc9A:
undetectable		 6ajiA-3mc9A:
16.00