SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mck C705 MONOCLONAL
HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 120
GLU H 158
HIS H 209
 None
 0.76A 3g1uB-3mckH:
undetectable		 3g1uB-3mckH:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3mck C705 MONOCLONAL
HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR H  54
HIS H  52
ARG H  60
 None
 1.17A 4e7bC-3mckH:
undetectable		 4e7bC-3mckH:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3mck C705 MONOCLONAL
HEAVY CHAIN
(Mus
musculus) 		5 / 12 PHE H  27
SER H  25
LEU H   4
VAL H  36
THR H  31
 None
 1.19A 4eckB-3mckH:
undetectable		 4eckB-3mckH:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3mck C705 MONOCLONAL
HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER H 213
ALA H 208
VAL H 207
 None
 0.58A 5eypA-3mckH:
undetectable		 5eypA-3mckH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 3mck C705 MONOCLONAL
HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER H 213
ALA H 208
VAL H 207
 None
 0.52A 5xiwC-3mckH:
undetectable		 5xiwC-3mckH:
16.30