SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mcp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		4 / 7 LEU A 154
GLY A 155
LEU A 242
PRO A 217
 None
None
None
GOL  A 366 ( 4.5A)
 0.93A 1ya4B-3mcpA:
undetectable		 1ya4B-3mcpA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 11 PHE A 342
ILE A 274
GLY A 243
LEU A 250
PHE A 158
 None
 1.16A 3t3rA-3mcpA:
undetectable		 3t3rA-3mcpA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 11 PHE A  73
PHE A  20
ASN A  50
LEU A  51
ALA A  57
 None
 1.45A 4dx7A-3mcpA:
1.1		 4dx7A-3mcpA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		4 / 7 TYR A  79
ALA A  77
ILE A  83
GLY A  82
 None
 0.62A 4eatA-3mcpA:
undetectable		 4eatA-3mcpA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		4 / 8 LEU A 242
ILE A 263
VAL A 340
GLY A 247
 None
 0.67A 4eq4B-3mcpA:
undetectable		 4eq4B-3mcpA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 9 GLY A 151
GLY A 155
PHE A 158
LEU A 154
GLY A 265
 None
 1.25A 4kqiA-3mcpA:
undetectable		 4kqiA-3mcpA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 12 SER A 343
GLY A 128
ILE A  25
MET A 353
GLY A 354
 None
 0.98A 4r29D-3mcpA:
undetectable		 4r29D-3mcpA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 12 PHE A 158
VAL A 340
GLY A 247
ALA A 246
ILE A 274
 None
 0.95A 4xdrA-3mcpA:
undetectable		 4xdrA-3mcpA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.38A 5eeuU-3mcpA:
undetectable
5eeuV-3mcpA:
undetectable		 5eeuU-3mcpA:
13.19
5eeuV-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.38A 5eevU-3mcpA:
undetectable
5eevV-3mcpA:
undetectable		 5eevU-3mcpA:
13.19
5eevV-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.38A 5eewU-3mcpA:
undetectable
5eewV-3mcpA:
undetectable		 5eewU-3mcpA:
13.19
5eewV-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 9 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.42A 5eexQ-3mcpA:
undetectable
5eexR-3mcpA:
undetectable		 5eexQ-3mcpA:
13.19
5eexR-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.38A 5eexU-3mcpA:
undetectable
5eexV-3mcpA:
undetectable		 5eexU-3mcpA:
13.19
5eexV-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 9 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.43A 5eeyQ-3mcpA:
undetectable
5eeyR-3mcpA:
undetectable		 5eeyQ-3mcpA:
13.19
5eeyR-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.37A 5eeyU-3mcpA:
undetectable
5eeyV-3mcpA:
undetectable		 5eeyU-3mcpA:
13.19
5eeyV-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 9 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.42A 5eezQ-3mcpA:
undetectable
5eezR-3mcpA:
undetectable		 5eezQ-3mcpA:
13.19
5eezR-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.37A 5eezU-3mcpA:
undetectable
5eezV-3mcpA:
undetectable		 5eezU-3mcpA:
13.19
5eezV-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 9 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.42A 5ef0Q-3mcpA:
undetectable
5ef0R-3mcpA:
undetectable		 5ef0Q-3mcpA:
13.19
5ef0R-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.37A 5ef0U-3mcpA:
undetectable
5ef0V-3mcpA:
undetectable		 5ef0U-3mcpA:
13.19
5ef0V-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 9 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.42A 5ef1Q-3mcpA:
undetectable
5ef1R-3mcpA:
undetectable		 5ef1Q-3mcpA:
13.19
5ef1R-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.37A 5ef1U-3mcpA:
undetectable
5ef1V-3mcpA:
undetectable		 5ef1U-3mcpA:
13.19
5ef1V-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 9 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.42A 5ef2Q-3mcpA:
undetectable
5ef2R-3mcpA:
undetectable		 5ef2Q-3mcpA:
13.19
5ef2R-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.37A 5ef2U-3mcpA:
undetectable
5ef2V-3mcpA:
undetectable		 5ef2U-3mcpA:
13.19
5ef2V-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 9 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.42A 5ef3Q-3mcpA:
undetectable
5ef3R-3mcpA:
undetectable		 5ef3Q-3mcpA:
13.19
5ef3R-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 GLY A  28
ALA A 352
ILE A  25
THR A 127
SER A 350
 None
 1.37A 5ef3U-3mcpA:
undetectable
5ef3V-3mcpA:
undetectable		 5ef3U-3mcpA:
13.19
5ef3V-3mcpA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		4 / 8 LEU A  13
PHE A  73
ALA A  39
PHE A  90
 None
 0.94A 5m0oC-3mcpA:
undetectable		 5m0oC-3mcpA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 10 HIS A 362
LEU A 363
ALA A 359
SER A  70
GLY A 123
 None
 1.22A 5m5cE-3mcpA:
undetectable		 5m5cE-3mcpA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		5 / 12 PHE A  71
PHE A  20
ALA A  39
ALA A  41
LEU A  99
 None
 1.08A 6aybA-3mcpA:
undetectable		 6aybA-3mcpA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		4 / 7 ASN A 283
ALA A 284
GLU A 244
LEU A 279
 None
 1.01A 6ci6A-3mcpA:
2.4		 6ci6A-3mcpA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3mcp GLUCOKINASE
(Parabacteroides
distasonis) 		3 / 3 HIS A 362
ASN A 361
LEU A 360
 None
 0.90A 6f7lB-3mcpA:
undetectable		 6f7lB-3mcpA:
20.80