SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mcu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		5 / 12 ILE A   8
LEU A 179
GLY A   9
CYH A  87
LEU A   3
 None
 1.00A 1liiA-3mcuA:
2.3		 1liiA-3mcuA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A  37
VAL A 124
THR A 117
 None
 0.74A 2nmzA-3mcuA:
undetectable		 2nmzA-3mcuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A  37
VAL A 124
THR A 117
 None
 0.70A 2nnkA-3mcuA:
undetectable		 2nnkA-3mcuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A 170
VAL A 125
THR A 177
 None
 0.87A 2nnkA-3mcuA:
undetectable		 2nnkA-3mcuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		5 / 10 VAL A  89
GLY A   9
ILE A  61
LEU A  26
THR A  65
 None
 1.43A 3bexE-3mcuA:
undetectable
3bexF-3mcuA:
undetectable		 3bexE-3mcuA:
23.51
3bexF-3mcuA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		4 / 6 GLY A 156
THR A 130
GLU A 193
GLU A 161
 None
 0.89A 3fpjA-3mcuA:
3.8		 3fpjA-3mcuA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A  37
VAL A 124
THR A 117
 None
 0.69A 3k4vA-3mcuA:
undetectable		 3k4vA-3mcuA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A 170
VAL A 125
THR A 177
 None
 0.87A 3k4vA-3mcuA:
undetectable		 3k4vA-3mcuA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A  37
VAL A 124
THR A 117
 None
 0.63A 3k4vD-3mcuA:
undetectable		 3k4vD-3mcuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		5 / 10 LEU A  79
SER A 108
ILE A  70
PHE A  10
SER A  97
 None
 1.50A 3m0wE-3mcuA:
undetectable
3m0wF-3mcuA:
undetectable
3m0wG-3mcuA:
undetectable
3m0wH-3mcuA:
undetectable		 3m0wE-3mcuA:
22.68
3m0wF-3mcuA:
22.68
3m0wG-3mcuA:
22.68
3m0wH-3mcuA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		5 / 10 LEU A  79
SER A 108
ILE A  70
PHE A  10
SER A  97
 None
 1.46A 3m0wA-3mcuA:
undetectable
3m0wB-3mcuA:
undetectable
3m0wI-3mcuA:
undetectable
3m0wJ-3mcuA:
undetectable		 3m0wA-3mcuA:
22.68
3m0wB-3mcuA:
22.68
3m0wI-3mcuA:
22.68
3m0wJ-3mcuA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A 170
VAL A 125
THR A 177
 None
 0.75A 3ndtA-3mcuA:
undetectable		 3ndtA-3mcuA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A  37
VAL A 124
THR A 117
 None
 0.56A 3nduD-3mcuA:
undetectable		 3nduD-3mcuA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A  37
VAL A 124
THR A 117
 None
 0.73A 3pwrA-3mcuA:
undetectable		 3pwrA-3mcuA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A  37
VAL A 124
THR A 117
 None
 0.65A 3tl9A-3mcuA:
undetectable		 3tl9A-3mcuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ARG A 170
VAL A 125
THR A 177
 None
 0.87A 3tl9A-3mcuA:
undetectable		 3tl9A-3mcuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		5 / 12 PRO A  78
GLU A  77
VAL A  39
ILE A  70
ILE A  73
 None
 0.95A 4a99A-3mcuA:
5.1
4a99C-3mcuA:
4.7		 4a99A-3mcuA:
19.70
4a99C-3mcuA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		5 / 6 VAL A 110
ALA A 114
LEU A 126
THR A  94
LEU A  93
 None
 1.24A 4o0uA-3mcuA:
undetectable		 4o0uA-3mcuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		4 / 8 GLU A  62
PHE A  10
GLY A   9
TYR A  19
 None
 0.94A 5flcB-3mcuA:
undetectable		 5flcB-3mcuA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		4 / 8 GLU A  62
PHE A  10
GLY A   9
TYR A  19
 None
 0.94A 5flcF-3mcuA:
undetectable		 5flcF-3mcuA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		4 / 6 GLU A  35
ARG A  37
LEU A  85
ARG A   7
 None
 1.23A 5l6eA-3mcuA:
undetectable
5l6eB-3mcuA:
2.2		 5l6eA-3mcuA:
18.26
5l6eB-3mcuA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		3 / 3 ASN A 149
TYR A 151
CYH A  87
 None
 1.02A 5lsuB-3mcuA:
undetectable		 5lsuB-3mcuA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3mcu DIPICOLINATE
SYNTHASE, B CHAIN
(Bacillus
cereus) 		5 / 9 ASP A  86
GLY A  75
SER A  72
VAL A  39
ILE A  70
 None
 1.45A 6giqA-3mcuA:
undetectable
6giqE-3mcuA:
undetectable
6giqI-3mcuA:
undetectable		 6giqA-3mcuA:
19.00
6giqE-3mcuA:
19.83
6giqI-3mcuA:
16.15