SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3md2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3md2 MATRIX PROTEIN 1
(Influenza
A
virus) 		5 / 12 GLY A 122
ALA A 123
SER A 126
GLY A 129
LEU A 130
 None
 0.85A 1fe2A-3md2A:
undetectable		 1fe2A-3md2A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3md2 MATRIX PROTEIN 1
(Influenza
A
virus) 		4 / 8 ASP A 156
ALA A 155
SER A  13
TYR A  10
 None
 0.97A 3rodA-3md2A:
undetectable		 3rodA-3md2A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3md2 MATRIX PROTEIN 1
(Influenza
A
virus) 		5 / 12 GLY A 122
ALA A 123
SER A 126
GLY A 129
LEU A 130
 None
 0.77A 4e1gA-3md2A:
undetectable		 4e1gA-3md2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3md2 MATRIX PROTEIN 1
(Influenza
A
virus) 		5 / 12 GLY A 122
ALA A 123
SER A 126
GLY A 129
LEU A 130
 None
 0.78A 4e1gB-3md2A:
undetectable		 4e1gB-3md2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3md2 MATRIX PROTEIN 1
(Influenza
A
virus) 		5 / 10 LEU A  52
LEU A  28
GLY A  61
THR A  56
VAL A  63
 None
 1.35A 4yb6A-3md2A:
undetectable
4yb6D-3md2A:
undetectable		 4yb6A-3md2A:
19.86
4yb6D-3md2A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3md2 MATRIX PROTEIN 1
(Influenza
A
virus) 		5 / 10 LEU A  52
LEU A  28
GLY A  61
THR A  56
VAL A  63
 None
 1.34A 4yb6D-3md2A:
undetectable
4yb6E-3md2A:
undetectable		 4yb6D-3md2A:
19.86
4yb6E-3md2A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3md2 MATRIX PROTEIN 1
(Influenza
A
virus) 		4 / 4 CYH A 127
LEU A 103
LEU A 146
ALA A 142
 None
 1.13A 5hpuA-3md2A:
undetectable
5hpuB-3md2A:
undetectable		 5hpuA-3md2A:
13.10
5hpuB-3md2A:
16.67