SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3md3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3md3 NUCLEAR AND
CYTOPLASMIC
POLYADENYLATED
RNA-BINDING PROTEIN
PUB1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 130
ALA A 131
VAL A  97
VAL A 120
LEU A  82
 None
 1.17A 2g78A-3md3A:
undetectable		 2g78A-3md3A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3md3 NUCLEAR AND
CYTOPLASMIC
POLYADENYLATED
RNA-BINDING PROTEIN
PUB1
(Saccharomyces
cerevisiae) 		5 / 11 GLN A 155
VAL A 208
SER A 209
THR A 161
LEU A 178
 GOL  A 244 ( 3.7A)
None
None
None
None
 1.36A 5jh7D-3md3A:
undetectable		 5jh7D-3md3A:
16.55