SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mdn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		4 / 5 SER A 208
ARG A 199
HIS A 100
HIS A 111
 None
 1.48A 1s19A-3mdnA:
undetectable		 1s19A-3mdnA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		5 / 12 MET A 242
PHE A 255
ALA A 250
ALA A 164
ALA A 162
 None
 1.30A 2x2nA-3mdnA:
undetectable		 2x2nA-3mdnA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 SER A 224
VAL A 223
VAL A  46
GLY A  45
 None
 0.98A 4mk4A-3mdnA:
undetectable		 4mk4A-3mdnA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ASP A  50
VAL A  73
ALA A  74
GLY A  56
SER A  79
 None
 1.20A 4mm5A-3mdnA:
undetectable		 4mm5A-3mdnA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ASP A  50
VAL A  73
ALA A  74
GLY A  56
SER A  79
 None
 1.22A 4mmbA-3mdnA:
undetectable		 4mmbA-3mdnA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ASP A  50
VAL A  73
ALA A  74
GLY A  56
SER A  79
 None
 1.24A 4mmeA-3mdnA:
undetectable		 4mmeA-3mdnA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ASP A  50
VAL A  73
ALA A  74
GLY A  56
SER A  79
 None
 1.25A 4mmeB-3mdnA:
undetectable		 4mmeB-3mdnA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ASP A  50
VAL A  73
ALA A  74
GLY A  56
SER A  79
 None
 1.21A 4mmfA-3mdnA:
0.7		 4mmfA-3mdnA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		5 / 9 ASP A  50
VAL A  73
ALA A  74
GLY A  56
SER A  79
 None
 1.22A 4mmfB-3mdnA:
undetectable		 4mmfB-3mdnA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		3 / 3 MET A 183
GLU A 171
LEU A 170
 None
 0.73A 4v2oB-3mdnA:
undetectable		 4v2oB-3mdnA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		3 / 3 GLY A  80
LEU A  81
HIS A   8
 None
 0.63A 5u63A-3mdnA:
undetectable		 5u63A-3mdnA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		3 / 3 GLY A  80
LEU A  81
HIS A   8
 None
 0.67A 5u63B-3mdnA:
undetectable		 5u63B-3mdnA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3mdn GLUTAMINE
AMINOTRANSFERASE
CLASS-II DOMAIN
PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 THR A  10
GLY A   9
GLY A 219
SER A 214
 None
 0.73A 5vw9A-3mdnA:
undetectable		 5vw9A-3mdnA:
22.78