SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mdo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 6 CYH A  35
ASP A  91
VAL A  95
HIS A  53
 None
CA  A 391 ( 2.9A)
None
PGE  A 403 (-4.4A)
 1.43A 1ekjG-3mdoA:
undetectable
1ekjH-3mdoA:
undetectable		 1ekjG-3mdoA:
20.56
1ekjH-3mdoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
GLY A 108
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.84A 1hxbA-3mdoA:
undetectable		 1hxbA-3mdoA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.98A 1hxbB-3mdoA:
undetectable		 1hxbB-3mdoA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 4 LEU A 220
GLY A 241
ASP A 246
TYR A 219
 None
None
None
PEG  A 400 ( 4.2A)
 1.40A 1oxrA-3mdoA:
undetectable		 1oxrA-3mdoA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.06A 1rl8B-3mdoA:
undetectable		 1rl8B-3mdoA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.81A 2bpxB-3mdoA:
undetectable		 2bpxB-3mdoA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 7 SER A 190
SER A 189
ASN A 335
GLN A 292
 None
None
CL  A 394 (-3.9A)
None
 1.08A 2cmlA-3mdoA:
undetectable		 2cmlA-3mdoA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 8 SER A 190
SER A 189
ASN A 335
GLN A 292
 None
None
CL  A 394 (-3.9A)
None
 1.08A 2cmlD-3mdoA:
undetectable		 2cmlD-3mdoA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 6 LEU A 377
TYR A 388
ILE A 379
GLY A 290
 None
 0.90A 2du8A-3mdoA:
undetectable		 2du8A-3mdoA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 6 LEU A 377
TYR A 388
ILE A 379
GLY A 290
 None
 0.90A 2du8B-3mdoA:
undetectable		 2du8B-3mdoA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.97A 2f81B-3mdoA:
undetectable		 2f81B-3mdoA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.96A 2f81B-3mdoA:
undetectable		 2f81B-3mdoA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 11 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.91A 2fxeB-3mdoA:
undetectable		 2fxeB-3mdoA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 122
ILE A 107
ILE A  80
 None
None
None
ACT  A 395 (-4.3A)
None
 0.80A 2hs1A-3mdoA:
undetectable		 2hs1A-3mdoA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 1.01A 2hs2B-3mdoA:
undetectable		 2hs2B-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 9 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.12A 2idwB-3mdoA:
undetectable		 2idwB-3mdoA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.96A 2ienB-3mdoA:
undetectable		 2ienB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.04A 2nmzA-3mdoA:
undetectable		 2nmzA-3mdoA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.05A 2nmzB-3mdoA:
undetectable		 2nmzB-3mdoA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.82A 2o4lB-3mdoA:
undetectable		 2o4lB-3mdoA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		3 / 3 GLY A  56
ASP A  55
SER A 161
 None
CA  A 390 ( 3.0A)
None
 0.59A 2qhfA-3mdoA:
undetectable		 2qhfA-3mdoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 11 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.87A 2r5qB-3mdoA:
undetectable		 2r5qB-3mdoA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.10A 2rkfB-3mdoA:
undetectable		 2rkfB-3mdoA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.09A 2rkgA-3mdoA:
undetectable		 2rkgA-3mdoA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.10A 3bvbB-3mdoA:
undetectable		 3bvbB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.84A 3d1xA-3mdoA:
undetectable		 3d1xA-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.95A 3d1xB-3mdoA:
undetectable		 3d1xB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.96A 3d1xB-3mdoA:
undetectable		 3d1xB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 10 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.00A 3ekpC-3mdoA:
undetectable		 3ekpC-3mdoA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 10 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.06A 3ekpD-3mdoA:
undetectable		 3ekpD-3mdoA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 11 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.09A 3ektC-3mdoA:
undetectable		 3ektC-3mdoA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 11 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.95A 3ektD-3mdoA:
undetectable		 3ektD-3mdoA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 10 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.10A 3ekvA-3mdoA:
undetectable		 3ekvA-3mdoA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 11 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.93A 3em4A-3mdoA:
undetectable		 3em4A-3mdoA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.85A 3jvyB-3mdoA:
undetectable		 3jvyB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.09A 3k4vA-3mdoA:
undetectable		 3k4vA-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.04A 3k4vB-3mdoA:
undetectable		 3k4vB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.97A 3k4vC-3mdoA:
undetectable		 3k4vC-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.90A 3k4vD-3mdoA:
undetectable		 3k4vD-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.94A 3k4vD-3mdoA:
undetectable		 3k4vD-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.97A 3k4vD-3mdoA:
undetectable		 3k4vD-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 1.06A 3mwsA-3mdoA:
undetectable		 3mwsA-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.13A 3ndtA-3mdoA:
undetectable		 3ndtA-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.03A 3ndtB-3mdoA:
undetectable		 3ndtB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.90A 3nduA-3mdoA:
undetectable		 3nduA-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.86A 3nduB-3mdoA:
undetectable		 3nduB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.96A 3nduB-3mdoA:
undetectable		 3nduB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.98A 3nduB-3mdoA:
undetectable		 3nduB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 11 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.07A 3nu3B-3mdoA:
undetectable		 3nu3B-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 9 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.08A 3nu4B-3mdoA:
undetectable		 3nu4B-3mdoA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 9 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.07A 3nujB-3mdoA:
undetectable		 3nujB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 9 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.09A 3nuoB-3mdoA:
undetectable		 3nuoB-3mdoA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.86A 3oxcA-3mdoA:
undetectable		 3oxcA-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.97A 3pwmB-3mdoA:
undetectable		 3pwmB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.96A 3pwrB-3mdoA:
undetectable		 3pwrB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.95A 3pwrB-3mdoA:
undetectable		 3pwrB-3mdoA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 10 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.00A 3s43B-3mdoA:
undetectable		 3s43B-3mdoA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 10 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 1.01A 3s43B-3mdoA:
undetectable		 3s43B-3mdoA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.11A 3s54B-3mdoA:
undetectable		 3s54B-3mdoA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 5 TYR A  65
LEU A 242
LYS A 243
ARG A 212
 None
None
PEG  A 400 (-3.0A)
None
 1.38A 3sudD-3mdoA:
undetectable		 3sudD-3mdoA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.95A 3tkgA-3mdoA:
undetectable		 3tkgA-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.96A 3tkgA-3mdoA:
undetectable		 3tkgA-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.97A 3tkgB-3mdoA:
undetectable		 3tkgB-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.97A 3tkgB-3mdoA:
undetectable		 3tkgB-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.99A 3tkgD-3mdoA:
undetectable		 3tkgD-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.98A 3tkwA-3mdoA:
undetectable		 3tkwA-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.11A 3tkwB-3mdoA:
undetectable		 3tkwB-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.06A 3tl9A-3mdoA:
undetectable		 3tl9A-3mdoA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		3 / 3 SER A 356
ASP A  90
ASP A  83
 None
 0.84A 3uj7A-3mdoA:
undetectable		 3uj7A-3mdoA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 10 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.13A 4dqfB-3mdoA:
undetectable		 4dqfB-3mdoA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 251
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 0.99A 4hlaA-3mdoA:
undetectable		 4hlaA-3mdoA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 11 LEU A 251
GLY A 256
ALA A 255
ILE A 319
ILE A 248
 None
 0.98A 4hlaB-3mdoA:
undetectable		 4hlaB-3mdoA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 10 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.07A 4ll3B-3mdoA:
undetectable		 4ll3B-3mdoA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 10 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.09A 4ll3A-3mdoA:
undetectable		 4ll3A-3mdoA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 9 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.09A 4rvjB-3mdoA:
undetectable		 4rvjB-3mdoA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 9 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.10A 4rvjD-3mdoA:
undetectable		 4rvjD-3mdoA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 8 GLY A 202
SER A 261
SER A 205
ASN A 200
 None
 1.02A 4wryA-3mdoA:
undetectable		 4wryA-3mdoA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 8 GLY A 202
SER A 261
SER A 205
ASN A 200
 None
 1.03A 4wrzA-3mdoA:
undetectable		 4wrzA-3mdoA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		4 / 8 GLY A 202
SER A 261
SER A 205
ASN A 200
 None
 0.97A 4ws1A-3mdoA:
undetectable		 4ws1A-3mdoA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.08A 5e5kA-3mdoA:
undetectable		 5e5kA-3mdoA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 ASP A 160
GLY A  56
MET A  87
ASN A  88
ASN A 206
 None
 1.30A 5kbwA-3mdoA:
undetectable		 5kbwA-3mdoA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		5 / 12 GLY A  58
ASP A 160
ILE A 107
VAL A  76
ILE A  80
 None
None
ACT  A 395 (-4.3A)
None
None
 0.87A 5kqxA-3mdoA:
undetectable		 5kqxA-3mdoA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 3mdo PUTATIVE
PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 251
GLY A 256
ALA A 255
ASP A 246
ILE A 319
ILE A 248
 None
 1.09A 5t2zB-3mdoA:
undetectable		 5t2zB-3mdoA:
13.70