SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 (-3.3A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.51A 1a4lA-3mduA:
21.5		 1a4lA-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
PHE A  60
HIS A 232
HIS A 269
ASP A 320
 ZN  A 454 (-3.3A)
None
ZN  A 454 (-3.3A)
None
ZN  A 454 (-2.9A)
 1.32A 1a4lA-3mduA:
21.5		 1a4lA-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.40A 1a4lA-3mduA:
21.5		 1a4lA-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
PHE A  60
HIS A 232
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
None
ZN  A 454 (-3.3A)
None
ZN  A 454 (-2.9A)
 1.30A 1a4lA-3mduA:
21.5		 1a4lA-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.39A 1a4lB-3mduA:
21.3		 1a4lB-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
PHE A  60
HIS A 232
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
None
ZN  A 454 (-3.3A)
None
ZN  A 454 (-2.9A)
 1.35A 1a4lB-3mduA:
21.3		 1a4lB-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  56
HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.53A 1a4lC-3mduA:
21.4		 1a4lC-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  56
HIS A  58
PHE A  60
HIS A 232
HIS A 269
ASP A 320
 ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
None
ZN  A 454 (-3.3A)
None
ZN  A 454 (-2.9A)
 1.33A 1a4lC-3mduA:
21.4		 1a4lC-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.34A 1a4lD-3mduA:
21.3		 1a4lD-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
PHE A  60
HIS A 232
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
None
ZN  A 454 (-3.3A)
None
ZN  A 454 (-2.9A)
 1.29A 1a4lD-3mduA:
21.3		 1a4lD-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 315
HIS A 230
LEU A  55
ALA A 371
GLY A 373
 None
 1.33A 1cmaA-3mduA:
undetectable
1cmaB-3mduA:
undetectable		 1cmaA-3mduA:
17.91
1cmaB-3mduA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 371
GLY A 373
LEU A 315
HIS A 230
LEU A  55
 None
 1.31A 1cmcA-3mduA:
undetectable
1cmcB-3mduA:
undetectable		 1cmcA-3mduA:
17.91
1cmcB-3mduA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 121
HIS A 206
HIS A 232
HIS A  56
ASP A 320
 NGQ  A 455 (-3.8A)
NGQ  A 455 (-3.9A)
ZN  A 454 (-3.3A)
ZN  A 454 (-3.3A)
ZN  A 454 (-2.9A)
 1.13A 1ituA-3mduA:
11.3		 1ituA-3mduA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 121
HIS A 206
HIS A 232
HIS A  56
ASP A 320
 NGQ  A 455 (-3.8A)
NGQ  A 455 (-3.9A)
ZN  A 454 (-3.3A)
ZN  A 454 (-3.3A)
ZN  A 454 (-2.9A)
 1.13A 1ituB-3mduA:
9.4		 1ituB-3mduA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		3 / 3 GLU A  98
GLU A 118
LEU A 194
 GOL  A 457 (-3.5A)
None
None
 0.72A 1v8bA-3mduA:
undetectable		 1v8bA-3mduA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 159
ILE A 177
ARG A 209
GLY A 163
 None
None
NGQ  A 455 (-3.1A)
None
 1.31A 1ve9A-3mduA:
undetectable		 1ve9A-3mduA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  78
TYR A  86
TYR A 121
ARG A 209
 NGQ  A 455 (-4.2A)
None
NGQ  A 455 (-3.8A)
NGQ  A 455 (-3.1A)
 1.47A 1xqlA-3mduA:
4.5
1xqlB-3mduA:
4.4		 1xqlA-3mduA:
23.91
1xqlB-3mduA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 121
ARG A 209
PHE A  78
TYR A  86
 NGQ  A 455 (-3.8A)
NGQ  A 455 (-3.1A)
NGQ  A 455 (-4.2A)
None
 1.46A 1xqlA-3mduA:
4.9
1xqlB-3mduA:
4.4		 1xqlA-3mduA:
23.91
1xqlB-3mduA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 ILE A 231
LEU A 252
ALA A 234
GLU A 239
 None
 1.34A 1xvaA-3mduA:
undetectable
1xvaB-3mduA:
undetectable		 1xvaA-3mduA:
21.54
1xvaB-3mduA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 331
GLY A 318
CYH A 266
ASN A  54
ALA A 371
 None
 1.27A 2bm9B-3mduA:
undetectable		 2bm9B-3mduA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  49
TYR A 361
ASP A 403
ALA A 404
ALA A 400
 None
 1.04A 2br4F-3mduA:
undetectable		 2br4F-3mduA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A 332
LEU A 331
ILE A 317
LEU A  55
TYR A 113
 None
 1.24A 2bxmA-3mduA:
undetectable		 2bxmA-3mduA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 159
ILE A 177
ARG A 209
GLY A 163
 None
None
NGQ  A 455 (-3.1A)
None
 1.29A 2du8G-3mduA:
undetectable		 2du8G-3mduA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 159
ILE A 177
ARG A 209
GLY A 163
 None
None
NGQ  A 455 (-3.1A)
None
 1.31A 2du8J-3mduA:
undetectable		 2du8J-3mduA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 176
SER A 170
ARG A 174
ALA A  90
 None
 1.04A 2o01A-3mduA:
undetectable		 2o01A-3mduA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 298
HIS A  56
HIS A  58
HIS A 232
 NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
 0.82A 2ow9A-3mduA:
undetectable		 2ow9A-3mduA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.33A 2pgfA-3mduA:
22.4		 2pgfA-3mduA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  56
HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.43A 2pgrA-3mduA:
22.5		 2pgrA-3mduA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 4 VAL A 240
ASP A 300
LEU A 290
ARG A 250
 None
 1.07A 2ziaA-3mduA:
undetectable		 2ziaA-3mduA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 ASN A  54
HIS A  56
HIS A  58
HIS A 232
LEU A 155
 None
ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
None
 1.19A 3bl1A-3mduA:
undetectable		 3bl1A-3mduA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 152
ALA A 148
ILE A 100
VAL A 116
ILE A 150
 None
 1.03A 3el1A-3mduA:
undetectable		 3el1A-3mduA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 10 GLU A 295
LEU A 315
LEU A 290
MET A  52
LEU A 360
 None
 1.41A 3erdB-3mduA:
undetectable		 3erdB-3mduA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.33A 3iaiA-3mduA:
undetectable		 3iaiA-3mduA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.32A 3iaiB-3mduA:
undetectable		 3iaiB-3mduA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.32A 3iaiC-3mduA:
undetectable		 3iaiC-3mduA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 HIS A 232
LEU A 104
PHE A  60
VAL A  89
 ZN  A 454 (-3.3A)
None
None
None
 0.92A 3jwqC-3mduA:
undetectable		 3jwqC-3mduA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 298
HIS A  56
HIS A  58
HIS A 232
 NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
 0.87A 3kecA-3mduA:
undetectable		 3kecA-3mduA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 387
ILE A   4
ALA A   3
ALA A  30
ALA A 385
 None
 0.92A 3mdvB-3mduA:
undetectable		 3mdvB-3mduA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 GLU A 235
TYR A  86
GLN A  61
ASP A 320
 NGQ  A 455 (-2.9A)
None
NGQ  A 455 (-3.4A)
ZN  A 454 (-2.9A)
 1.00A 3mjrD-3mduA:
undetectable		 3mjrD-3mduA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 ALA A 144
GLU A 118
ALA A  59
MET A 108
 GOL  A 457 ( 4.2A)
None
None
None
 1.41A 3r9tC-3mduA:
undetectable		 3r9tC-3mduA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 159
VAL A 211
SER A 207
GLY A 163
 None
 1.22A 3v4tA-3mduA:
undetectable
3v4tD-3mduA:
undetectable		 3v4tA-3mduA:
22.44
3v4tD-3mduA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  10
LEU A  49
LEU A 405
MET A 355
 None
 0.86A 3vhuA-3mduA:
undetectable		 3vhuA-3mduA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 THR A 294
ASN A 297
GLY A 299
ASP A 300
 None
 1.32A 3w9tE-3mduA:
undetectable		 3w9tE-3mduA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 298
HIS A  56
HIS A  58
HIS A 232
 NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
 0.81A 4a7bA-3mduA:
undetectable		 4a7bA-3mduA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  55
HIS A 230
HIS A 269
HIS A 232
 None
None
None
ZN  A 454 (-3.3A)
 1.27A 4a7bB-3mduA:
undetectable		 4a7bB-3mduA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLN A  61
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 NGQ  A 455 (-3.4A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.50A 4aqlA-3mduA:
38.0		 4aqlA-3mduA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLN A  61
LEU A 298
HIS A 232
GLU A 235
HIS A 269
 NGQ  A 455 (-3.4A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.29A 4aqlA-3mduA:
38.0		 4aqlA-3mduA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 425
ILE A  23
TRP A 427
SER A   2
 None
 1.14A 4d33A-3mduA:
undetectable		 4d33A-3mduA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 425
ILE A  23
TRP A 427
SER A   2
 None
 1.14A 4d33B-3mduA:
undetectable		 4d33B-3mduA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 255
VAL A 261
HIS A 269
PHE A 119
GLY A 318
 None
 1.20A 4hvcB-3mduA:
undetectable		 4hvcB-3mduA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 SER A 200
LEU A  55
ALA A 117
THR A 153
 None
 1.06A 4ikkA-3mduA:
undetectable
4ikkB-3mduA:
undetectable		 4ikkA-3mduA:
12.86
4ikkB-3mduA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		3 / 3 ILE A  97
MET A  88
ARG A  91
 None
 0.84A 4lnwA-3mduA:
undetectable		 4lnwA-3mduA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		3 / 3 ILE A  97
MET A  88
ARG A  91
 None
 0.86A 4lnxA-3mduA:
undetectable		 4lnxA-3mduA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 406
ASN A 407
MET A  52
LEU A 331
 None
 1.16A 4okbA-3mduA:
undetectable		 4okbA-3mduA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 406
ASN A 407
MET A  52
LEU A 331
 None
 1.15A 4okxA-3mduA:
undetectable		 4okxA-3mduA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 255
VAL A 261
HIS A 269
PHE A 119
GLY A 318
 None
 1.13A 4q15A-3mduA:
undetectable		 4q15A-3mduA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
HIS A 269
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
None
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.47A 4r88A-3mduA:
29.3		 4r88A-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
HIS A 269
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.03A 4r88A-3mduA:
29.3		 4r88A-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.33A 4r88B-3mduA:
30.1		 4r88B-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.54A 4r88B-3mduA:
30.1		 4r88B-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.01A 4r88B-3mduA:
30.1		 4r88B-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.31A 4r88C-3mduA:
29.6		 4r88C-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.54A 4r88C-3mduA:
29.6		 4r88C-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.00A 4r88C-3mduA:
29.6		 4r88C-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.31A 4r88D-3mduA:
29.6		 4r88D-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.54A 4r88D-3mduA:
29.6		 4r88D-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.01A 4r88D-3mduA:
29.6		 4r88D-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.29A 4r88E-3mduA:
29.2		 4r88E-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.56A 4r88E-3mduA:
29.2		 4r88E-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.05A 4r88E-3mduA:
29.2		 4r88E-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.32A 4r88F-3mduA:
29.7		 4r88F-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.55A 4r88F-3mduA:
29.7		 4r88F-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.02A 4r88F-3mduA:
29.7		 4r88F-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 367
GLY A 316
GLY A 289
LEU A 365
ALA A 369
 None
 0.95A 4uciA-3mduA:
undetectable		 4uciA-3mduA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 367
GLY A 316
GLY A 289
LEU A 365
ALA A 369
 None
 0.96A 4uciB-3mduA:
undetectable		 4uciB-3mduA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 367
GLY A 316
GLY A 289
LEU A 365
ALA A 369
 None
 0.95A 4uckA-3mduA:
undetectable		 4uckA-3mduA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 406
GLY A  14
LEU A  11
LEU A 405
ALA A  47
 None
 1.07A 4wnuA-3mduA:
undetectable		 4wnuA-3mduA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 290
LEU A 267
ALA A 270
ALA A 282
ALA A 286
 None
 0.82A 4x20B-3mduA:
undetectable		 4x20B-3mduA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 255
VAL A 261
HIS A 269
PHE A 119
GLY A 318
 None
 1.18A 4ydqA-3mduA:
undetectable		 4ydqA-3mduA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 427
ILE A  23
SER A   2
 None
 1.02A 5gqbA-3mduA:
2.8		 5gqbA-3mduA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  11
ALA A 380
LEU A  29
ALA A 366
GLY A 377
 None
 0.90A 5jglB-3mduA:
undetectable		 5jglB-3mduA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.28A 5jn8B-3mduA:
undetectable		 5jn8B-3mduA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A  61
HIS A  58
HIS A  56
LEU A 298
THR A 294
 NGQ  A 455 (-3.4A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
None
 1.40A 5jn8C-3mduA:
undetectable		 5jn8C-3mduA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 10 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.29A 5jn8D-3mduA:
undetectable		 5jn8D-3mduA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 ASN A  54
HIS A  56
HIS A  58
HIS A 232
LEU A 155
 None
ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
None
 1.31A 5jnaD-3mduA:
undetectable		 5jnaD-3mduA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 240
ASP A 241
HIS A 272
ALA A 234
THR A 294
 None
 1.44A 5m54B-3mduA:
undetectable		 5m54B-3mduA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 ILE A  23
ALA A  30
LEU A  29
ILE A  32
 None
 0.83A 5mvmB-3mduA:
undetectable
5mvmC-3mduA:
undetectable		 5mvmB-3mduA:
12.01
5mvmC-3mduA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 118
ALA A 117
LEU A 152
TYR A 105
 None
 1.15A 5phhA-3mduA:
undetectable		 5phhA-3mduA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 277
ASP A 307
ALA A 282
SER A 284
GLY A 289
 None
 1.18A 5syeB-3mduA:
2.3		 5syeB-3mduA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 255
VAL A 261
HIS A 269
PHE A 119
GLY A 318
 None
 1.15A 5xipA-3mduA:
undetectable		 5xipA-3mduA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 255
VAL A 261
HIS A 269
PHE A 119
GLY A 318
 None
 1.23A 5xipC-3mduA:
undetectable		 5xipC-3mduA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 255
VAL A 261
HIS A 269
PHE A 119
GLY A 318
 None
 1.16A 5xiqA-3mduA:
undetectable		 5xiqA-3mduA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 255
VAL A 261
HIS A 269
PHE A 119
GLY A 318
 None
 1.12A 5xiqD-3mduA:
undetectable		 5xiqD-3mduA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 290
LEU A 267
ALA A 270
ALA A 282
ALA A 286
 None
 0.94A 5xiwB-3mduA:
2.9		 5xiwB-3mduA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 186
ASP A 133
PRO A 134
ARG A 189
 None
 1.33A 6fgdA-3mduA:
undetectable		 6fgdA-3mduA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A 271
ALA A 234
ALA A 273
GLY A 289
ALA A 288
 None
 0.87A 6hwdK-3mduA:
undetectable
6hwdL-3mduA:
undetectable		 6hwdK-3mduA:
12.78
6hwdL-3mduA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A 271
ALA A 234
ALA A 273
GLY A 289
ALA A 288
 None
 0.87A 6hwdY-3mduA:
undetectable
6hwdZ-3mduA:
undetectable		 6hwdY-3mduA:
12.78
6hwdZ-3mduA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.30A 6n91A-3mduA:
21.2		 6n91A-3mduA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
LEU A 298
HIS A 232
GLU A 235
HIS A 269
 ZN  A 454 ( 3.2A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.25A 6n91A-3mduA:
21.2		 6n91A-3mduA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.30A 6n91B-3mduA:
21.2		 6n91B-3mduA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
LEU A 298
HIS A 232
GLU A 235
HIS A 269
 ZN  A 454 ( 3.2A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.24A 6n91B-3mduA:
21.2		 6n91B-3mduA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 369
GLY A 368
LEU A  55
GLY A 151
 None
 0.78A 6nm4A-3mduA:
undetectable		 6nm4A-3mduA:
17.26