SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3me8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		5 / 9 ASP A  91
VAL A  67
TRP A  66
GLY A  62
GLY A  94
 None
 1.30A 1bcuH-3me8A:
undetectable		 1bcuH-3me8A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		4 / 6 HIS A 126
PHE A 115
ASP A  73
PRO A  35
 None
 1.49A 1ilqA-3me8A:
undetectable
1ilqC-3me8A:
undetectable		 1ilqA-3me8A:
18.90
1ilqC-3me8A:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		3 / 3 GLY A  89
TRP A  95
VAL A  97
 None
 0.78A 3n62B-3me8A:
undetectable		 3n62B-3me8A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		3 / 3 GLY A  89
TRP A  95
VAL A  97
 None
 0.76A 3n65B-3me8A:
undetectable		 3n65B-3me8A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		3 / 3 GLY A  89
TRP A  95
VAL A  97
 None
 0.76A 3n66B-3me8A:
undetectable		 3n66B-3me8A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		5 / 9 ILE A 113
LEU A 133
ILE A  31
ILE A  32
ILE A  68
 None
 1.04A 3zosA-3me8A:
undetectable		 3zosA-3me8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		5 / 12 ASP A  76
ASP A  80
HIS A  39
PHE A 124
PHE A  72
 None
 1.31A 4wh5A-3me8A:
undetectable		 4wh5A-3me8A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		5 / 12 ILE A  55
ILE A  32
VAL A  54
ASN A 128
ILE A 143
 None
 1.08A 5lg3J-3me8A:
undetectable		 5lg3J-3me8A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3me8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Aquifex
aeolicus) 		5 / 12 ILE A  90
LEU A 133
ILE A 143
ILE A  47
PHE A  84
 None
 1.01A 5mugA-3me8A:
undetectable		 5mugA-3me8A:
21.03