SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 5 PHE A 140
VAL A  35
VAL A 104
ASP A 101
 None
 1.45A 1dz6B-3memA:
undetectable		 1dz6B-3memA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 THR A 355
SER A 344
GLY A 317
GLY A 311
LEU A 396
 None
 1.06A 1jg4A-3memA:
undetectable		 1jg4A-3memA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A 217
LEU A 255
ALA A 447
VAL A 252
GLN A 220
 None
 1.36A 1kt4A-3memA:
undetectable		 1kt4A-3memA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 LEU A 217
LEU A 255
ALA A 447
VAL A 252
GLN A 220
 None
 1.35A 1kt6A-3memA:
undetectable		 1kt6A-3memA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 LEU A 217
LEU A 255
ALA A 447
VAL A 252
GLN A 220
 None
 1.31A 1kt7A-3memA:
undetectable		 1kt7A-3memA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 MET A 369
LEU A 309
ALA A 260
LEU A 259
VAL A 252
 None
 1.20A 2c12C-3memA:
undetectable		 2c12C-3memA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 8 ILE A 347
SER A 344
ASP A 343
ARG A  33
 None
 0.88A 2cdqA-3memA:
undetectable		 2cdqA-3memA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 THR A 374
VAL A 373
LEU A 313
ALA A 360
 None
 0.91A 2e1qA-3memA:
undetectable		 2e1qA-3memA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 THR A 374
VAL A 373
LEU A 313
ALA A 360
 None
 0.95A 2e1qC-3memA:
undetectable		 2e1qC-3memA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 ILE A 445
ARG A 406
THR A 404
LEU A 410
 None
 1.00A 2einN-3memA:
undetectable
2einW-3memA:
undetectable		 2einN-3memA:
20.84
2einW-3memA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 ARG A 441
LEU A 395
ALA A 286
GLU A 437
LEU A 403
 None
 1.32A 2v0mA-3memA:
undetectable		 2v0mA-3memA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 ARG A 441
LEU A 395
ALA A 286
GLU A 437
LEU A 403
 None
 1.37A 2v0mD-3memA:
undetectable		 2v0mD-3memA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 ILE A 445
ARG A 406
THR A 404
LEU A 410
 None
 0.87A 3ag1N-3memA:
undetectable
3ag1W-3memA:
undetectable		 3ag1N-3memA:
20.84
3ag1W-3memA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 8 THR A 374
VAL A 373
LEU A 313
ALA A 360
 None
 0.89A 3ax7A-3memA:
undetectable		 3ax7A-3memA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 ILE A 445
GLY A 450
TYR A 230
LEU A 312
 None
 0.91A 3elzA-3memA:
undetectable		 3elzA-3memA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 THR A 374
VAL A 373
LEU A 313
ALA A 360
 None
 0.92A 3uniA-3memA:
undetectable		 3uniA-3memA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		6 / 9 LEU A 114
LEU A 121
LEU A  90
ALA A  10
LEU A  93
LEU A  84
 None
 1.19A 4z91F-3memA:
undetectable
4z91G-3memA:
undetectable
4z91H-3memA:
undetectable
4z91I-3memA:
undetectable
4z91J-3memA:
undetectable		 4z91F-3memA:
24.11
4z91G-3memA:
24.11
4z91H-3memA:
24.11
4z91I-3memA:
24.11
4z91J-3memA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 LYS A  61
ARG A  62
HIS A 138
 None
 1.24A 4zbrA-3memA:
undetectable		 4zbrA-3memA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 PRO A   4
PRO A  88
LEU A  87
LEU A 112
 None
 0.95A 5tl8A-3memA:
undetectable		 5tl8A-3memA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 TYR A 278
LEU A 183
LEU A 265
ILE A 359
ALA A 360
 None
 1.21A 5v0vA-3memA:
undetectable		 5v0vA-3memA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 ILE A 445
ARG A 406
THR A 404
LEU A 410
 None
 1.03A 5zcoN-3memA:
undetectable
5zcoW-3memA:
undetectable		 5zcoN-3memA:
20.84
5zcoW-3memA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 ARG A 356
HIS A 314
ARG A 400
 None
 1.01A 6dwdD-3memA:
3.8		 6dwdD-3memA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 8 MET A 253
ILE A 193
VAL A 222
SER A 216
 None
 1.09A 6fbvC-3memA:
undetectable		 6fbvC-3memA:
17.26