SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mep'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3mep UNCHARACTERIZED
PROTEIN ECA2234
(Pectobacterium
atrosepticum) 		4 / 4 GLY A 167
VAL A  54
GLY A  86
THR A  87
 None
 0.84A 3ib2A-3mepA:
undetectable		 3ib2A-3mepA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3mep UNCHARACTERIZED
PROTEIN ECA2234
(Pectobacterium
atrosepticum) 		5 / 12 PHE A 165
VAL A  54
GLY A  56
ILE A 141
ALA A  94
 None
 0.89A 3sufB-3mepA:
undetectable		 3sufB-3mepA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3mep UNCHARACTERIZED
PROTEIN ECA2234
(Pectobacterium
atrosepticum) 		4 / 8 PHE A  73
THR A 118
ILE A  96
GLY A 106
 None
 0.88A 5nzxA-3mepA:
undetectable		 5nzxA-3mepA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3mep UNCHARACTERIZED
PROTEIN ECA2234
(Pectobacterium
atrosepticum) 		4 / 7 PHE A  73
THR A 118
ILE A  96
GLY A 106
 None
 0.90A 5nzyA-3mepA:
undetectable		 5nzyA-3mepA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 3mep UNCHARACTERIZED
PROTEIN ECA2234
(Pectobacterium
atrosepticum) 		4 / 5 GLN A  79
ASP A  78
SER A 172
ARG A 175
 None
 1.29A 5w4zA-3mepA:
undetectable		 5w4zA-3mepA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 3mep UNCHARACTERIZED
PROTEIN ECA2234
(Pectobacterium
atrosepticum) 		5 / 11 PHE A  39
VAL A  54
MET A 169
THR A 110
VAL A 108
 None
 1.31A 6hcoA-3mepA:
undetectable
6hcoB-3mepA:
undetectable		 6hcoA-3mepA:
13.51
6hcoB-3mepA:
13.51