SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3meq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 9 GLY A  64
GLY A  88
ALA A 130
THR A 116
HIS A  65
 None
None
None
None
ZN  A 401 ( 3.2A)
 1.20A 1gtfD-3meqA:
undetectable
1gtfE-3meqA:
undetectable		 1gtfD-3meqA:
10.66
1gtfE-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.82A 1muiB-3meqA:
undetectable		 1muiB-3meqA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 THR A 164
SER A 264
VAL A 198
VAL A 215
ALA A 196
 None
 1.16A 1q23H-3meqA:
undetectable
1q23I-3meqA:
undetectable		 1q23H-3meqA:
20.11
1q23I-3meqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 VAL A 263
LEU A 275
GLY A 255
ALA A 253
LEU A 265
 None
 1.08A 1r9oA-3meqA:
undetectable		 1r9oA-3meqA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  88
HIS A 137
ALA A 130
ILE A  89
GLY A  84
 None
 1.05A 1utdE-3meqA:
undetectable
1utdF-3meqA:
undetectable		 1utdE-3meqA:
10.66
1utdF-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 11 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.89A 2aquB-3meqA:
undetectable		 2aquB-3meqA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.85A 2bpxB-3meqA:
undetectable		 2bpxB-3meqA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 11 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.82A 2fxeB-3meqA:
undetectable		 2fxeB-3meqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.70A 2o4sA-3meqA:
undetectable		 2o4sA-3meqA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		6 / 12 GLY A 117
GLY A  88
GLY A  67
GLY A 123
GLU A  66
HIS A 137
 None
 1.41A 2oxtB-3meqA:
2.9		 2oxtB-3meqA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		4 / 8 THR A 108
VAL A 155
THR A 156
VAL A 163
 None
None
NAI  A 601 (-3.0A)
None
 0.92A 2qbmA-3meqA:
undetectable		 2qbmA-3meqA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 ILE A  36
ALA A 125
GLY A  64
VAL A  41
GLY A  40
 None
 0.93A 2qe6B-3meqA:
4.9		 2qe6B-3meqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 VAL A 185
ILE A 177
GLY A 178
GLY A 179
VAL A 310
 None
None
NAI  A 601 (-3.3A)
NAI  A 601 (-3.5A)
None
 0.97A 2r5pA-3meqA:
undetectable		 2r5pA-3meqA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.86A 2r5pB-3meqA:
undetectable		 2r5pB-3meqA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 VAL A 185
ILE A 177
GLY A 178
GLY A 179
VAL A 310
 None
None
NAI  A 601 (-3.3A)
NAI  A 601 (-3.5A)
None
 0.97A 2r5pC-3meqA:
undetectable		 2r5pC-3meqA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.86A 2r5pD-3meqA:
undetectable		 2r5pD-3meqA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		3 / 3 GLY A 123
GLY A 117
GLY A  64
 None
 0.43A 3bogC-3meqA:
undetectable		 3bogC-3meqA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.85A 3bvbA-3meqA:
undetectable		 3bvbA-3meqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.72A 3d1xA-3meqA:
undetectable		 3d1xA-3meqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.82A 3d1yA-3meqA:
undetectable		 3d1yA-3meqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.79A 3jvyB-3meqA:
undetectable		 3jvyB-3meqA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.86A 3k4vA-3meqA:
undetectable		 3k4vA-3meqA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.86A 3k4vB-3meqA:
undetectable		 3k4vB-3meqA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 11 ALA A 312
THR A 313
ALA A 184
GLY A 181
ALA A 153
 None
 0.93A 3mg0K-3meqA:
undetectable
3mg0L-3meqA:
undetectable		 3mg0K-3meqA:
22.16
3mg0L-3meqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.83A 3ndtA-3meqA:
undetectable		 3ndtA-3meqA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.82A 3ndtB-3meqA:
undetectable		 3ndtB-3meqA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.87A 3nu3A-3meqA:
undetectable		 3nu3A-3meqA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.78A 3oxcA-3meqA:
undetectable		 3oxcA-3meqA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 ALA A  38
ILE A 147
GLY A  88
ILE A  89
VAL A 339
 None
 1.01A 3t3cB-3meqA:
undetectable		 3t3cB-3meqA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.89A 3tkgD-3meqA:
undetectable		 3tkgD-3meqA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.86A 3tkwB-3meqA:
undetectable		 3tkwB-3meqA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.86A 3tl9A-3meqA:
undetectable		 3tl9A-3meqA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 9 ILE A  89
GLY A  67
VAL A 120
THR A 116
GLY A 117
 None
 1.35A 4acaB-3meqA:
2.6
4acaC-3meqA:
3.3		 4acaB-3meqA:
23.79
4acaC-3meqA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A 123
GLY A  64
ILE A  36
ASN A 121
VAL A 128
 None
 1.01A 4fr0A-3meqA:
5.7		 4fr0A-3meqA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		4 / 8 ALA A  49
ASP A 321
ILE A 322
ILE A  19
 None
 0.92A 4ndnD-3meqA:
undetectable		 4ndnD-3meqA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		4 / 5 ILE A 147
LEU A 302
GLU A  66
VAL A 292
 None
None
None
NAI  A 601 (-3.4A)
 1.01A 4nkxB-3meqA:
undetectable		 4nkxB-3meqA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		4 / 7 MET A 329
HIS A  65
CYH A 152
GLY A  40
 NAI  A 601 ( 4.5A)
ZN  A 401 ( 3.2A)
ZN  A 401 (-2.2A)
None
 1.05A 5a5zC-3meqA:
undetectable		 5a5zC-3meqA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  69
LEU A 342
SER A  39
VAL A  34
VAL A 128
 None
 0.91A 5dpdA-3meqA:
6.2		 5dpdA-3meqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 LEU A 138
HIS A  80
VAL A  81
VAL A  71
VAL A  34
 None
 1.08A 5dpdA-3meqA:
6.2		 5dpdA-3meqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  69
LEU A 342
SER A  39
VAL A  34
VAL A 128
 None
 1.01A 5dpdB-3meqA:
4.2		 5dpdB-3meqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.04A 5eevA-3meqA:
undetectable
5eevB-3meqA:
undetectable		 5eevA-3meqA:
10.66
5eevB-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.04A 5eewA-3meqA:
undetectable
5eewB-3meqA:
undetectable		 5eewA-3meqA:
10.66
5eewB-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.04A 5eexA-3meqA:
undetectable
5eexB-3meqA:
undetectable		 5eexA-3meqA:
10.66
5eexB-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.04A 5eeyA-3meqA:
undetectable
5eeyB-3meqA:
undetectable		 5eeyA-3meqA:
10.66
5eeyB-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.04A 5eezA-3meqA:
undetectable
5eezB-3meqA:
undetectable		 5eezA-3meqA:
10.66
5eezB-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.04A 5ef0A-3meqA:
undetectable
5ef0B-3meqA:
undetectable		 5ef0A-3meqA:
10.66
5ef0B-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.05A 5ef1A-3meqA:
undetectable
5ef1B-3meqA:
undetectable		 5ef1A-3meqA:
10.66
5ef1B-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.04A 5ef2A-3meqA:
undetectable
5ef2B-3meqA:
undetectable		 5ef2A-3meqA:
10.66
5ef2B-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 10 GLY A  84
GLY A  88
HIS A 137
ALA A 130
ILE A  89
 None
 1.04A 5ef3A-3meqA:
undetectable
5ef3B-3meqA:
undetectable		 5ef3A-3meqA:
10.66
5ef3B-3meqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		3 / 3 GLY A  97
CYH A 102
CYH A  99
 ZN  A 501 ( 4.9A)
ZN  A 501 (-2.4A)
ZN  A 501 (-2.3A)
 0.97A 5inzB-3meqA:
undetectable		 5inzB-3meqA:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A  40
ILE A  62
GLY A 117
VAL A  34
ILE A  36
 None
 0.76A 5kqxA-3meqA:
undetectable		 5kqxA-3meqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 ILE A  89
GLY A  67
ILE A  32
ALA A 130
VAL A  71
 None
 1.02A 5n0wB-3meqA:
1.6		 5n0wB-3meqA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 ALA A 244
VAL A 245
GLY A 179
ALA A 312
ALA A 153
 NAI  A 601 (-3.7A)
NAI  A 601 (-4.3A)
NAI  A 601 (-3.5A)
None
None
 1.09A 5n5dA-3meqA:
7.0		 5n5dA-3meqA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 3meq ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING
(Brucella
suis) 		5 / 12 GLY A 176
ASP A 199
ILE A 200
ASP A 201
ALA A 249
 NAI  A 601 (-3.4A)
NAI  A 601 (-2.9A)
NAI  A 601 (-4.2A)
None
NAI  A 601 (-3.6A)
 0.82A 6bq4A-3meqA:
6.1		 6bq4A-3meqA:
12.71