SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mez'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3mez MANNOSE-SPECIFIC
LECTIN 3 CHAIN 1
MANNOSE-SPECIFIC
LECTIN 3 CHAIN 2
(Crocus
vernus) 		5 / 11 ILE A 104
GLY B  89
HIS B  65
LEU B  63
GLY B  86
 None
 1.27A 2fn1A-3mezA:
undetectable		 2fn1A-3mezA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3mez MANNOSE-SPECIFIC
LECTIN 3 CHAIN 1
MANNOSE-SPECIFIC
LECTIN 3 CHAIN 2
(Crocus
vernus;
Crocus
vernus) 		5 / 12 THR B 111
LEU A   5
ASN A  15
LEU A  54
LEU A  17
 None
 1.23A 3fsuA-3mezB:
undetectable		 3fsuA-3mezB:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3mez MANNOSE-SPECIFIC
LECTIN 3 CHAIN 2
(Crocus
vernus) 		3 / 3 ARG B  31
ASP B  17
ASP B  33
 None
 0.81A 3jayA-3mezB:
undetectable		 3jayA-3mezB:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3mez MANNOSE-SPECIFIC
LECTIN 3 CHAIN 1
MANNOSE-SPECIFIC
LECTIN 3 CHAIN 2
(Crocus
vernus;
Crocus
vernus) 		4 / 7 ASP B  25
THR B  23
ILE B  97
ASP A   1
 None
None
FMT  B 115 ( 4.2A)
None
 1.02A 4pcuA-3mezB:
undetectable		 4pcuA-3mezB:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 3mez MANNOSE-SPECIFIC
LECTIN 3 CHAIN 1
MANNOSE-SPECIFIC
LECTIN 3 CHAIN 2
(Crocus
vernus) 		4 / 5 LEU A  56
ALA A  88
LEU A   5
VAL B 102
 None
 1.12A 5cr1A-3mezA:
undetectable		 5cr1A-3mezA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3mez MANNOSE-SPECIFIC
LECTIN 3 CHAIN 2
(Crocus
vernus) 		3 / 3 THR B  78
THR B  84
LEU B  63
 None
 0.62A 5m66D-3mezB:
undetectable		 5m66D-3mezB:
13.23