SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mf3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 9 VAL A 193
GLY A 192
ALA A 208
ILE A 209
GLU A 153
 None
 1.12A 1cetA-3mf3A:
undetectable		 1cetA-3mf3A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 8 CYH A  42
HIS A  98
CYH A 101
GLY A 102
GLY A 103
 CO  A 230 (-2.2A)
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
None
 0.28A 1ekjA-3mf3A:
19.5
1ekjB-3mf3A:
18.9		 1ekjA-3mf3A:
27.87
1ekjB-3mf3A:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		4 / 8 CYH A  42
HIS A  98
CYH A 101
GLY A 103
 CO  A 230 (-2.2A)
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
 0.94A 1ekjA-3mf3A:
19.5
1ekjB-3mf3A:
18.9		 1ekjA-3mf3A:
27.87
1ekjB-3mf3A:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 8 CYH A  42
VAL A  66
HIS A  98
CYH A 101
GLY A 102
 CO  A 230 (-2.2A)
None
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
 0.30A 1ekjA-3mf3A:
19.5
1ekjB-3mf3A:
18.9		 1ekjA-3mf3A:
27.87
1ekjB-3mf3A:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		4 / 7 CYH A  42
HIS A  98
GLY A 102
GLY A 103
 CO  A 230 (-2.2A)
CO  A 230 (-2.9A)
None
None
 0.37A 1ekjE-3mf3A:
19.2
1ekjF-3mf3A:
19.1		 1ekjE-3mf3A:
27.87
1ekjF-3mf3A:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		4 / 8 CYH A  42
VAL A  66
GLY A 102
GLY A 103
 CO  A 230 (-2.2A)
None
None
None
 0.26A 1ekjE-3mf3A:
19.2
1ekjF-3mf3A:
19.1		 1ekjE-3mf3A:
27.87
1ekjF-3mf3A:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 8 CYH A  42
HIS A  98
CYH A 101
GLY A 102
GLY A 103
 CO  A 230 (-2.2A)
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
None
 0.31A 1ekjG-3mf3A:
19.2
1ekjH-3mf3A:
19.4		 1ekjG-3mf3A:
27.87
1ekjH-3mf3A:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		4 / 6 CYH A  42
VAL A  66
HIS A  98
CYH A 101
 CO  A 230 (-2.2A)
None
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
 0.27A 1ekjG-3mf3A:
19.2
1ekjH-3mf3A:
19.4		 1ekjG-3mf3A:
27.87
1ekjH-3mf3A:
27.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 10 CYH A  42
ASP A  44
HIS A  98
GLY A 103
ALA A 107
 CO  A 230 (-2.2A)
CO  A 230 (-3.1A)
CO  A 230 (-2.9A)
None
None
 1.17A 3ucjA-3mf3A:
24.4		 3ucjA-3mf3A:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 10 CYH A  42
HIS A  98
CYH A 101
GLY A 103
ALA A 107
 CO  A 230 (-2.2A)
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
None
 1.11A 3ucjA-3mf3A:
24.4		 3ucjA-3mf3A:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 10 CYH A  42
VAL A  66
HIS A  98
CYH A 101
ALA A 107
 CO  A 230 (-2.2A)
None
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
 0.89A 3ucjA-3mf3A:
24.4		 3ucjA-3mf3A:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		6 / 10 CYH A  42
VAL A  66
HIS A  98
CYH A 101
GLY A 102
ALA A 106
 CO  A 230 (-2.2A)
None
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
None
 0.45A 3ucjA-3mf3A:
24.4		 3ucjA-3mf3A:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 10 CYH A  42
ASP A  44
HIS A  98
GLY A 103
ALA A 107
 CO  A 230 (-2.2A)
CO  A 230 (-3.1A)
CO  A 230 (-2.9A)
None
None
 1.21A 3ucjB-3mf3A:
24.6		 3ucjB-3mf3A:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 10 CYH A  42
HIS A  98
CYH A 101
GLY A 103
ALA A 107
 CO  A 230 (-2.2A)
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
None
 1.13A 3ucjB-3mf3A:
24.6		 3ucjB-3mf3A:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		5 / 10 CYH A  42
VAL A  66
HIS A  98
CYH A 101
ALA A 107
 CO  A 230 (-2.2A)
None
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
 0.88A 3ucjB-3mf3A:
24.6		 3ucjB-3mf3A:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		6 / 10 CYH A  42
VAL A  66
HIS A  98
CYH A 101
GLY A 102
ALA A 106
 CO  A 230 (-2.2A)
None
CO  A 230 (-2.9A)
CO  A 230 (-2.1A)
None
None
 0.47A 3ucjB-3mf3A:
24.6		 3ucjB-3mf3A:
38.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 3mf3 CARBONIC ANHYDRASE 2
(Haemophilus
influenzae) 		4 / 7 VAL A  70
ILE A  94
VAL A  85
VAL A 164
 None
 0.83A 3ufnB-3mf3A:
undetectable		 3ufnB-3mf3A:
18.02