SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3mfn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_A_DVAA6_0 (MINI-GRAMICIDIN A)	3mfn	UNCHARACTERIZED PROTEIN (Dyadobacter fermentans)	3 / 3	ALA A 132 VAL A 127 TRP A 126	None	0.88A	1kqeA-3mfnA: undetectable 1kqeE-3mfnA: undetectable	1kqeA-3mfnA: 5.65 1kqeE-3mfnA: 5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_B_DVAB6_0 (MINI-GRAMICIDIN A)	3mfn	UNCHARACTERIZED PROTEIN (Dyadobacter fermentans)	3 / 3	ALA A 132 VAL A 127 TRP A 126	None	0.87A	1kqeB-3mfnA: undetectable 1kqeD-3mfnA: undetectable	1kqeB-3mfnA: 5.65 1kqeD-3mfnA: 5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_D_DVAD6_0 (MINI-GRAMICIDIN A)	3mfn	UNCHARACTERIZED PROTEIN (Dyadobacter fermentans)	3 / 3	TRP A 126 ALA A 132 VAL A 127	None	0.89A	1kqeB-3mfnA: undetectable 1kqeD-3mfnA: undetectable	1kqeB-3mfnA: 5.65 1kqeD-3mfnA: 5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_E_DVAE6_0 (MINI-GRAMICIDIN A)	3mfn	UNCHARACTERIZED PROTEIN (Dyadobacter fermentans)	3 / 3	TRP A 126 ALA A 132 VAL A 127	None	0.88A	1kqeA-3mfnA: undetectable 1kqeE-3mfnA: undetectable	1kqeA-3mfnA: 5.65 1kqeE-3mfnA: 5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_B_SAMB301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	3mfn	UNCHARACTERIZED PROTEIN (Dyadobacter fermentans)	5 / 12	LYS A 71 ASN A 79 ASP A 60 ALA A 58 ALA A 16	None	1.25A	2br4B-3mfnA: undetectable	2br4B-3mfnA: 21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_A_HSMA1161_1 (ALLERGEN ARG R 1)	3mfn	UNCHARACTERIZED PROTEIN (Dyadobacter fermentans)	4 / 5	VAL A 44 TYR A 38 VAL A 113 ASP A 109	None	1.02A	2x45A-3mfnA: undetectable	2x45A-3mfnA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_C_HSMC1161_1 (ALLERGEN ARG R 1)	3mfn	UNCHARACTERIZED PROTEIN (Dyadobacter fermentans)	4 / 5	VAL A 44 TYR A 38 VAL A 113 ASP A 109	None	1.05A	2x45C-3mfnA: undetectable	2x45C-3mfnA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JI8_A_SRYA1601_1 (16S RRNA RIBOSOMAL PROTEIN S12)	3mfn	UNCHARACTERIZED PROTEIN (Dyadobacter fermentans)	3 / 3	LYS A 71 LYS A 65 TRP A 75	None	1.38A	4ji8L-3mfnA: undetectable	4ji8L-3mfnA: 24.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KQE_A_DVAA6_0","MINI-GRAMICIDIN A","3mfn","UNCHARACTERIZED PROTEIN","Dyadobacter fermentans",3,"ALA A 132;VAL A 127;TRP A 126","None","0.88A","1kqeA-3mfnA:undetectable;1kqeE-3mfnA:undetectable","1kqeA-3mfnA:5.65;1kqeE-3mfnA:5.65"],["1KQE_B_DVAB6_0","MINI-GRAMICIDIN A","3mfn","UNCHARACTERIZED PROTEIN","Dyadobacter fermentans",3,"ALA A 132;VAL A 127;TRP A 126","None","0.87A","1kqeB-3mfnA:undetectable;1kqeD-3mfnA:undetectable","1kqeB-3mfnA:5.65;1kqeD-3mfnA:5.65"],["1KQE_D_DVAD6_0","MINI-GRAMICIDIN A","3mfn","UNCHARACTERIZED PROTEIN","Dyadobacter fermentans",3,"TRP A 126;ALA A 132;VAL A 127","None","0.89A","1kqeB-3mfnA:undetectable;1kqeD-3mfnA:undetectable","1kqeB-3mfnA:5.65;1kqeD-3mfnA:5.65"],["1KQE_E_DVAE6_0","MINI-GRAMICIDIN A","3mfn","UNCHARACTERIZED PROTEIN","Dyadobacter fermentans",3,"TRP A 126;ALA A 132;VAL A 127","None","0.88A","1kqeA-3mfnA:undetectable;1kqeE-3mfnA:undetectable","1kqeA-3mfnA:5.65;1kqeE-3mfnA:5.65"],["2BR4_B_SAMB301_0","CEPHALOSPORIN HYDROXYLASE CMCI","3mfn","UNCHARACTERIZED PROTEIN","Dyadobacter fermentans",5,"LYS A  71;ASN A  79;ASP A  60;ALA A  58;ALA A  16","None","1.25A","2br4B-3mfnA:undetectable","2br4B-3mfnA:21.72"],["2X45_A_HSMA1161_1","ALLERGEN ARG R 1","3mfn","UNCHARACTERIZED PROTEIN","Dyadobacter fermentans",4,"VAL A  44;TYR A  38;VAL A 113;ASP A 109","None","1.02A","2x45A-3mfnA:undetectable","2x45A-3mfnA:19.75"],["2X45_C_HSMC1161_1","ALLERGEN ARG R 1","3mfn","UNCHARACTERIZED PROTEIN","Dyadobacter fermentans",4,"VAL A  44;TYR A  38;VAL A 113;ASP A 109","None","1.05A","2x45C-3mfnA:undetectable","2x45C-3mfnA:19.75"],["4JI8_A_SRYA1601_1","16S RRNA;RIBOSOMAL PROTEIN S12","3mfn","UNCHARACTERIZED PROTEIN","Dyadobacter fermentans",3,"LYS A  71;LYS A  65;TRP A  75","None","1.38A","4ji8L-3mfnA:undetectable","4ji8L-3mfnA:24.56"]]